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| (R)-(+)-Dropropizine Basic information |
| (R)-(+)-Dropropizine Chemical Properties |
| Melting point | 98-100° | | alpha | D25 -10° (c = 1.0 in ethanol) | | Boiling point | 412.7±34.0 °C(Predicted) | | density | 1.168±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Acetonitrile (Slightly), Methanol (Slightly) | | pka | 14.21±0.20(Predicted) | | form | neat | | color | White to Off-White | | CAS DataBase Reference | 99291-24-4(CAS DataBase Reference) |
| Toxicity | LD50 in mice, rats (mg/kg): 1287.2, 886.6 orally; 408.0, 401.3 i.p. (Borsa) |
| (R)-(+)-Dropropizine Usage And Synthesis |
| Description | Levodropropizine is an antitussive with antiinflammatory activity, the L-isomer of
dropropizine. Compared with the racemate, levodropropizine is reported to have less
sedative potential and better therapeutic index, while maintaining the the same efficacy
levels as an antitussive and antiinflammatory. | | Originator | Dompe (Italy) | | Uses | R-Form of Dropropizine (D681495). (R)-(+)-Dropropizine is a cough suppressive phenylpiperazine derivative. (R)-(+)-Dropropizine is an antitussive and central sedative therapeutic agent. | | Uses | receptor agonist, treatment of colds and allergic rhinitis | | Brand name | Levotus |
| (R)-(+)-Dropropizine Preparation Products And Raw materials |
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