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| Thionicotinamide adenine dinucleotide Basic information |
| Product Name: | Thionicotinamide adenine dinucleotide | | Synonyms: | THIONICOTINAMIDE ADENINE DINUCLEOTIDE;THIONICOTINAMIDE-DPN;THIO-NAD;adenosine 5'-(trihydrogen diphosphate), 5'->5'-ester with 3-(aminothioxomethyl)-1-beta-D-ribofuranosylpyridinium--ate;Thionicotinamide-NAD;beta-Thionicotinamide adenine dinucleotide, oxidised form 92+%;3-Thiocarbamoylpyridine adenine dinucleotide;3-Thionicotinamide adenine dinucleotide | | CAS: | 4090-29-3 | | MF: | C21H27N7O13P2S | | MW: | 679.49 | | EINECS: | 223-828-6 | | Product Categories: | nucleoside | | Mol File: | 4090-29-3.mol |
| Thionicotinamide adenine dinucleotide Chemical Properties |
| storage temp. | -20°C | | form | powder to crystal | | color | Light orange to Yellow to Green | | InChIKey | DQRRIGAXTAXHLR-NNYOXOHSSA-N | | CAS DataBase Reference | 4090-29-3 |
| Thionicotinamide adenine dinucleotide Usage And Synthesis |
| Description | Thionicotinamide adenine dinucleotide is an analog of NAD. Use of Thio-NAD instead of NAD as a substrate for NAD(+)-consuming enzymes is more advantageous since the reduced form of Thio-NAD exhibits a substantial increase in absorbance at 405 nM, the most commonly available wavelength on microplate readers. | | Uses | Thionicotinamide adenine dinucleotide has been used as a substrate analog in S-adenosyl-l-homocysteine (AdoHcy) hydrolases (SAHH) inhibition assay and in NAD+ glycohydrolase activity. | | Uses | Thionicotinamide adenine dinucleotide (thio-NAD) is a NAD (N407784) derivative used in the determination of Carnitine by an enzymic cycling method with carnitine dehydrogenase. | | Application | Thionicotinamide adenine dinucleotide (thio-NAD) is a NAD derivative used in the determination of Carnitine by an enzymic cycling method with carnitine dehydrogenase. | | Biological Activity | Thionicotinamide adenine dinucleotide (sNAD) is an analog of coenzyme nicotinamide adenine dinucleotide (NAD) and NADH. sNAD is a potential inhibitor of NAD+ kinase. NAD+ kinase modulates NAD levels, contributing to cytotoxicity in cancer cells. | | Biochem/physiol Actions | Thionicotinamide adenine dinucleotide (sNAD) is an analog of coenzyme nicotinamide adenine dinucleotide (NAD) and NADH. sNAD is a potential inhibitor of NAD+ kinase. NAD+ kinase modulates NAD levels, contributing to cytotoxicity in cancer cells. |
| Thionicotinamide adenine dinucleotide Preparation Products And Raw materials |
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