Triclabendazole

Triclabendazole
  • CAS No.:68786-66-3
Other grades of this product :
Triclabendazole Basic information
Product Name:Triclabendazole
Synonyms:FASINEX;CGA-89317;6-CHLORO-5-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-BENZIMIDAZOLE;5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-1H-BENZIMIDAZOLE;TRICLABENDAZOLE;5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1h-benzimidazol;Tricalbendazole;5-Chloro-6-(2,3-dichlorophenoxy)-2-methylthio-1H-benzimidazole, CGA-89317, Fasinex
CAS:68786-66-3
MF:C14H9Cl3N2OS
MW:359.66
EINECS:614-728-7
Product Categories:Veterinary drugs;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Pharmaceutical intermediate;68786-66-3
Mol File:68786-66-3.mol
Triclabendazole Chemical Properties
Melting point 175-176°C
Boiling point 240.6°C (rough estimate)
density 1.3875 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Acetonitrile (Slightly, Sonicated), Methanol (Slightly)
form neat
pka7.91±0.10(Predicted)
color White to Beige
Merck 14,9652
Stability:Stability
InChIKeyNQPDXQQQCQDHHW-UHFFFAOYSA-N
CAS DataBase Reference68786-66-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
RTECS DD6747000
HS Code 29339900
ToxicityLD50 oral in rabbit: 206mg/kg
MSDS Information
Triclabendazole Usage And Synthesis
DescriptionTriclabendazole is a benzimidazole anthelmintic. It eliminates both immature and adult flukes in a sheep model of F. hepatica infection when administered at a dose of 10 mg/kg. Triclabendazole (5 μM) also protects against glucose- or α-synuclein-induced apoptosis in S. cerevisiae via inhibition of adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A (PKA) nutrient sensing pathway.
Chemical PropertiesOff-White Solid
UsesAn anthelmintic (fasciola)
UsesTriclabendazole is classified under the category of ‘Anthelmintic flukicide for veterinary use.
UsesAn anthelmintic (fasciola).
Triclabendazole Preparation Products And Raw materials

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