Ethopabate

Ethopabate
  • CAS No.:59-06-3
Other grades of this product :
Ethopabate Basic information
Product Name:Ethopabate
Synonyms:Ethopabate, Vetranal;ETHOPABATE (4-ACETYLAMINO-2-ETHOXY-BENZOIC ACID METHYL ESTER);4-Acetamido-2-ethoxybenzoic acid, methyl ester;Ethopatate;Ethytpatate;METHYL 4-ACETAMIDO-2-ETHOXYBENZOATE;ETHOPABATE;4-ACETYLAMINO-2-ETHOXY-BENZOIC ACID METHYL ESTER
CAS:59-06-3
MF:C12H15NO4
MW:237.25
EINECS:200-414-3
Product Categories:NARDIL;animal pharmaceutical;Amines;Aromatics;Drug Analogues;Intermediates & Fine Chemicals;Aromatic Esters;Pharmaceuticals
Mol File:59-06-3.mol
Ethopabate Chemical Properties
Melting point 148-151 °C
Boiling point 426.1±35.0 °C(Predicted)
density 1.180±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka14.12±0.70(Predicted)
Merck 13,3781
CAS DataBase Reference59-06-3(CAS DataBase Reference)
EPA Substance Registry SystemEthopabate (59-06-3)
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 3
HS Code 2924296000
MSDS Information
ProviderLanguage
Ethopabate English
SigmaAldrich English
Ethopabate Usage And Synthesis
Chemical PropertiesWhite to Off-White Solid
UsesA supplementary drug that improves the coccidiostatic effect of nicarbazin and amprolium in order to cure coccidiosis in chickens.
Usesantidepressant
Clinical UseEthopabate is only a narrow anticoccidial spectrum drug against Eimeria acervulina. It has no or only slight activity against E. maxima, E. necatrix, E. tenella or E. brunetti. Today, ethopabate is applied only in combination with amprolium and sulfonamide.
Molecular InteractionsEthopabate is a 2-substituted PABA derivative (=4-acetamido-2-ethoxybenzoic acid methylester) and functions as a prodrug. Its activity becomes potentiated by pyrimethamine and antagonised by the simultaneous administration of PABA. Thus, the mode of action of ethopabate is similar to that of sulfonamides or sulfones.
Ethopabate Preparation Products And Raw materials
Raw materials3-Methyl-1-butanol
Preparation Products2-Ethoxy-4-amino-5-chlorobenzoic acid

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