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| 2-(4-Methylphenyl)propanoic acid Basic information |
| 2-(4-Methylphenyl)propanoic acid Chemical Properties |
| Melting point | 37-42 °C(lit.) | | Boiling point | 231.67°C (rough estimate) | | density | 1.0041 (rough estimate) | | refractive index | 1.518-1.52 | | Fp | >230 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 4.44±0.10(Predicted) | | color | White to Off-White Low-Melting | | BRN | 2251315 | | CAS DataBase Reference | 938-94-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 29163990 |
| 2-(4-Methylphenyl)propanoic acid Usage And Synthesis |
| Chemical Properties | clear yellow liquid after melting | | Uses | 2-(p-Tolyl)propionic acid is an impurity of Ibuprofen (I140000). Ibuprofen impurity D. | | Uses | 2-(p-Tolyl)propionic acid (Ibuprofen EP Impurity D) is an impurity of Ibuprofen (I140000). Ibuprofen impurity D. | | Synthesis Reference(s) | Synthesis, p. 231, 1984 DOI: 10.1055/s-1984-30784Tetrahedron Letters, 36, p. 5641, 1995 DOI: 10.1016/0040-4039(95)01035-G | | General Description | α,4-Dimethylphenylacetic acid is also referred to as 2-(4-methylphenyl)propanoic acid. It is an alkaline decomposition product of azalomycin-B, a macrolide antibiotic produced by Streptomyces hygroscopicus var. azalomyceticus. The reaction of pinonic acid with bromine in water affords 2-(4-methylphenyl)propanoic acid. |
| 2-(4-Methylphenyl)propanoic acid Preparation Products And Raw materials |
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