Bornyl acetate

Bornyl acetate
  • CAS No.:76-49-3

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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Bornyl acetate Basic information
Product Name:Bornyl acetate
Synonyms:1-BORNYLACETATE;Acetic acid isobornyl ester;(1,7,7-trimethyl-6-bicyclo[2.2.1]heptanyl) acetate;Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, acetate, (1R,2S,4R)-;1,7,7-Trimethylbicyclo[2.2.1]heptane-2-yl=acetate;Acetic acid 1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl;Acetic acid 1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl ester;Acetic acid isobornyl
CAS:76-49-3
MF:C12H20O2
MW:196.29
EINECS:200-964-4
Product Categories:A-B;Alphabetical Listings;Flavors and Fragrances;Inhibitors
Mol File:76-49-3.mol
Bornyl acetate Chemical Properties
Melting point 29°C
alpha -41 º (neat)
Boiling point 228-231 °C(lit.)
density 0.985 g/mL at 25 °C(lit.)
refractive index n20/D 1.4635(lit.)
FEMA 2159 | BORNYL ACETATE
Fp 192 °F
Merck 13,1329
JECFA Number1387
CAS DataBase Reference76-49-3
NIST Chemistry ReferenceBornyl acetate(76-49-3)
EPA Substance Registry SystemBornyl acetate (76-49-3)
Safety Information
WGK Germany 1
MSDS Information
ProviderLanguage
Acetic acid isobornyl ester English
SigmaAldrich English
Bornyl acetate Usage And Synthesis
Chemical PropertiesBornyl acetate occurs in its optically active forms and as a racemate in many essential oils. (1S,2R,4S)-(?)-Bornyl acetate is a characteristic component of most conifer oils. It has a camphoraceous, pine-needle-like odor. Both (1R,2S,4R)- (+)-bornyl acetate and (?)-bornyl acetate form colorless crystals; the racemate is a colorless liquid. Bornyl acetate is prepared by esterification of borneol with acetic anhydride or via the process described under borneol. Due to its characteristic pine-needle odor, bornyl acetate is frequently used in conifer needle compositions, soaps, bath products, room sprays, and pharmaceutical products.
Chemical PropertiesBornyl acetate has a fresh, strong, piney odor and a fresh, burning taste.
OccurrenceReported found in the oils of Abies canadensis, A. concolor, Picea canadensis, P. rubens, P. orientalis, Pinus densiflora, Larix americana, Callitris drum-mondi, Abies alba, Pinus punulio, Abies sibirica L., and in coriander, thyme and valerian oil; it has been identified in the essence from flowers of Chrysanthemum sincuse Sabin, in the distillate of Teucrium chamaedris L., and in the fresh rhizomes of Valeriana officinalis L.; d-bornyl acetate is found in the essential oils of Callitris glauca, C. robusta, C. gracilis, C. verrucosa and C. calcarata; the presence of acetate has been excluded from the essence of lavender and lavandin.
UsesAntineoplastic; radioactive agent.
Aroma threshold valuesDetection: 75 ppb to 1.38 ppm
Taste threshold valuesTaste characteristics at 10 ppm: camphoreous, woody, mentholic, berry and seedy with soapy, woody nuances.
Synthesisl-Bornyl acetate occurs naturally in many oils distilled from the leaves of plants of the family Pinaceae; d-bornyl acetate is found in the oils distilled from plants of the family Cupressaceae; bornyl acetate, therefore may be isolated by distillation and crystallization from these; however, it is commonly prepared by direct acetylation of borneol; the first synthesis dates to 1889.
Bornyl acetate Preparation Products And Raw materials
Raw materialsTurpentine oil
Preparation ProductsTerpinolene

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