Other grades of this product :
| Methyl 3-amino-2-pyrazinecarboxylate Basic information |
| Methyl 3-amino-2-pyrazinecarboxylate Chemical Properties |
| Melting point | 169-172 °C (lit.) | | Boiling point | 300.8±37.0 °C(Predicted) | | density | 1.319±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,2-8°C | | solubility | Chloroform, Methanol | | pka | -0.30±0.10(Predicted) | | form | Crystalline Powder | | color | Yellow | | BRN | 127495 | | InChIKey | INCSQLZZXBPATR-UHFFFAOYSA-N | | LogP | 0.2 at 20℃ and pH7 | | Surface tension | 73.3mN/m at 1g/L and 20℃ | | CAS DataBase Reference | 16298-03-6(CAS DataBase Reference) |
| Methyl 3-amino-2-pyrazinecarboxylate Usage And Synthesis |
| Chemical Properties | yellow crystalline powder | | Uses | Methyl 3-amino-2-pyrazinecarboxylate has been used in: - synthesis of 2-arylpteridin-4-ones and piperazine-derived 2-furan-2-yl-[1,2,4]triazolo[1,5-a] pyrazines
- reactions with isocyanates and aroyl chlorides for conversion to pteridinediones
| | Purification Methods | The ester forms yellow needles from H2O (100 parts using charcoal). If it contains the free acid (see IR), then dissolve it in CH2Cl2, wash it with saturated aqueous Na2CO3, brine, dry over MgSO4 filter, evaporate and recrystallise the residue. The free acid has m 203-204o (dec) [UV: Brown & Mason J Chem Soc 3443 1956] and pK1 <1 and pK2 3.70. The ammonium salt has m 232o(dec) (from aqueous Me2CO) and the amide has m 239.2o (from H2O) [Ellingson et al. J Am Chem Soc 67 1711 1945]. [Beilstein 25 III/IV 4412.] |
| Methyl 3-amino-2-pyrazinecarboxylate Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye