2',3'-O-ISOPROPYLIDENEURIDINE

2',3'-O-ISOPROPYLIDENEURIDINE
  • CAS No.:362-43-6
Other grades of this product :
2',3'-O-ISOPROPYLIDENEURIDINE Basic information
Product Name:2',3'-O-ISOPROPYLIDENEURIDINE
Synonyms:Uridine 2',3'-acetonide;Uridine, 2',3'-O-(1-methylethylidene)-;Uridine, 2',3'-O-isopropylidene-;2',3'-ISOPROPYLIDENEURIDENE;2,3-ISOPROPYLIDENE URIDINE;2',3'-ISOPROPYLIDENEURIDINE;2',3'-IPU;2',3'-O-ISOPROPYLIDENEURIDINE
CAS:362-43-6
MF:C12H16N2O6
MW:284.27
EINECS:206-647-7
Product Categories:API intermediates;Bases & Related Reagents;Nucleotides;Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides
Mol File:362-43-6.mol
2',3'-O-ISOPROPYLIDENEURIDINE Chemical Properties
Melting point 163-166 °C
Boiling point 426.76°C (rough estimate)
density 1.2932 (rough estimate)
refractive index 1.5460 (estimate)
storage temp. -20°C
solubility Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
form Fine Crystalline Powder or Needles
pka9.25±0.10(Predicted)
color White
BRN 32671
CAS DataBase Reference362-43-6(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29339900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
2',3'-O-ISOPROPYLIDENEURIDINE Usage And Synthesis
Description2',3'-Isopropylideneuridine has been shown to inhibit binding of pestivirus inhibitors by monoclonal antibodies. 2',3'-Isopropylideneuridine was also found to inhibit the replication of human immunodeficiency virus (HIV) in tissue culture by binding to the viral RNA polymerase and inhibiting its activity, preventing viral replication.
Chemical PropertiesWhite Needle-Like Crystals
Uses2′,3′-O-Isopropylideneuridine is used in the chemical synthesis of N-benzoylated uridine derivatives and N3-substituted 2′,3′-O-isopropylideneuridines with central nervous system (CNS) depressant activity.
Uses2',3'-O-Isopropylideneuridine can be used as a useful precursor for the preparation of nucleic acids.
2',3'-O-ISOPROPYLIDENEURIDINE Preparation Products And Raw materials
Preparation ProductsUTP-->3-METHYL URIDINE-->UDP

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