ACETYLCHOLINE BROMIDE

ACETYLCHOLINE BROMIDE
  • CAS No.:66-23-9
Other grades of this product :
ACETYLCHOLINE BROMIDE Basic information
Product Name:ACETYLCHOLINE BROMIDE
Synonyms:Acetylcholine bromide;2-(Acetyloxy)-N,N,N-trimethylethanaminium bromide;PRAGMOLINE;N-(2-HYDROXYETHYL)TRIMETHYLAMMONIUM BROMIDE ACETATE;2-ACETOXYETHYLTRIMETHYLAMMONIUM BROMIDE;ACH;ACETYLCHOLINE BROMIDE;(2-Hydroxyethyl)trimethylammoniumbromideacetate;2-(acetyloxy)-n,n,n-trimethyl-ethanaminiubromide
CAS:66-23-9
MF:C7H16BrNO2
MW:226.11
EINECS:200-622-4
Product Categories:Ammonium Bromides (Quaternary);Quaternary Ammonium Compounds
Mol File:66-23-9.mol
ACETYLCHOLINE BROMIDE Chemical Properties
Melting point 140-143 °C(lit.)
density 1.4246 (rough estimate)
refractive index 1.6120 (estimate)
storage temp. -20°C
solubility Methanol (Slightly), Water (Slightly)
form Solid
color Off-White
Water Solubility almost transparency
Sensitive Hygroscopic
Merck 14,86
BRN 3572117
CAS DataBase Reference66-23-9(CAS DataBase Reference)
EPA Substance Registry SystemAcetylcholine bromide (66-23-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS FZ9680000
3-8-10-23
HS Code 29379000
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
ACETYLCHOLINE BROMIDE Usage And Synthesis
Chemical PropertiesWHITE TO LIGHT BEIGE ADHERING CRYSTALLINE SOLID
UsesAcetylcholine is an endogenous neurotransmitter at cholinergic synapses that amplifies action potential of the sarcolemma thereby inducing muscle contractions. Acetylcholine bromide is used as an acetylcholine receptor agonist to identify, characterize and differentiate among types of cholinergic receptors. Acetylcholine bromide is used as an inhibitor to identify and characterize natural and mutated butyrylcholinesterase(s).
DefinitionChEBI: The bromide salt of acetylcholine.
Biochem/physiol ActionsEndogenous neurotransmitter at cholinergic synapses; amplifies action potential of the sarcolemma thereby inducing muscle contractions.
Purification MethodsThe bromide is a hygroscopic solid, but less so than the hydrochloride salt. It crystallises from EtOH as prisms. Some hydrolysis occurs in boiling EtOH, particularly if it contains some H2O. It can also be recrystallised from EtOH or MeOH by adding dry Et2O. [Heilbronn Acta Chem Scand 12 1492 1958, Beilstein 4 IV 1446.]
ACETYLCHOLINE BROMIDE Preparation Products And Raw materials
Raw materialsEthanol-->Acetic anhydride-->Isopropyl alcohol-->Trimethylamine-->ACETALDEHYDE AMMONIA-->2-Bromoethanol-->Acetyl bromide

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