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| 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID Basic information |
| Product Name: | 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID | | Synonyms: | Chrysanthemum Acid;2,2,3,3-Tetramethylcyclopropylcarboxylic acid;2，2，3，3-tetramethylcyclopropan carboxylic acid;Chrysanthemic acid;2,2,3,3-Tetramethyl-1-cyclopropanecarboxylic acid;2,2,3,3-Tetramethylcyclopropane-1-carboxylic acid;3-Carboxy-1,1,2,2-tetramethylcyclopropane;2,2,3,3-Tetramethylcyclopropanecarboxylic acid 99% | | CAS: | 15641-58-4 | | MF: | C8H14O2 | | MW: | 142.2 | | EINECS: | 627-306-2 | | Product Categories: | C8;Carbonyl Compounds;Cyclopropanes;Simple 3-Membered Ring Compounds;Carboxylic Acids | | Mol File: | 15641-58-4.mol |
| 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID Chemical Properties |
| Melting point | 120-121 °C(lit.) | | Boiling point | 204.8±8.0 °C(Predicted) | | density | 0.999±0.06 g/cm3(Predicted) | | RTECS | GZ2083500 | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Oil | | pka | 5.20±0.44(Predicted) | | color | White to Off-White | | Water Solubility | Slightly soluble in water. Soluble in methanol, ethanol and acetonitrile. | | CAS DataBase Reference | 15641-58-4(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29162090 |
| 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID Usage And Synthesis |
| Chemical Properties | White powder | | Uses | 2,2,3,3-Tetramethylcyclopropanecarboxylic Acid is the cyclic analogue of the antiepileptic drug, Valproic Acid (V094750). 2,2,3,3-Tetramethylcyclopropanecarboxylic Acid is the starting material used in the synthesis of CNS-active compounds. | | Uses | 2,2,3,3-Tetramethylcyclopropanecarboxylic acid was used as a starting material for the synthesis of central nervous system-active compounds. | | Definition | ChEBI: A monocarboxylic acid consisting of cyclopropanecarboxylic acid having four methyl substituents. | | General Description | 2,2,3,3-Tetramethylcyclopropanecarboxylic acid is an inactive cyclopropyl analog of valproic acid (major antiepileptic drug). Inhibition of histone deacetylases and tumor cells cytotoxicities of 2,2,3,3-tetramethylcyclopropanecarboxylic acid was studied. |
| 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID Preparation Products And Raw materials |
| Raw materials | Ethanol-->Sodium nitrite-->Glycine-->PROPYLENE-->Ethyl 2,2,3,3-tetramethylcyclopropane-carboxylate-->tricarbon dioxide-->Dispiro[2.1.2.1]octane-4,8-dione, 1,1,2,2,6,6,7,7-octamethyl--->Cyclopropene, 1,3,3-trimethyl--->Methyl 2,2,3,3-tetraMethylcyclopropanecarboxylate-->CARBON DIOXIDE-->3-PHENOXYBENZALDEHYDE CYANOHYDRIN, 70 WT% SOLUTION IN ETHER-->2,3-Dimethyl-2-butene-->METHYLMAGNESIUM IODIDE-->Ethyl diazoacetate | | Preparation Products | Fenpropathrin-->Fenpropathrin-->2，2，3，3-tetramethyl cyclopropane carboxynyl chloride |
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