D(+)-Pipecolinic acid

D(+)-Pipecolinic acid
  • CAS No.:1723-00-8
Other grades of this product :
D(+)-Pipecolinic acid Basic information
Product Name:D(+)-Pipecolinic acid
Synonyms:(R)-2-Piperidine-2-carboxylic acid;D-Homoproline≥ 99% (Assay);D-HomoPro-OH;H-L-PIP-OH;H-HOMOPRO-OH;H-HOPRO-OH;H-PIPERIDINE-2-CARBOXYLIC ACID;HOMOPROLINE
CAS:1723-00-8
MF:C6H11NO2
MW:129.16
EINECS:217-024-4
Product Categories:Amino Acids & Derivatives;Intermediates;Amino ACIDS SERIES;chiral;Chiral Reagents;Heterocycles;Amino Acids and Derivatives
Mol File:1723-00-8.mol
D(+)-Pipecolinic acid Chemical Properties
Melting point 272 °C(lit.)
alpha 26.5 º (c=5,water 25 ºC)
Boiling point 239.22°C (rough estimate)
density 1.1426 (rough estimate)
refractive index 1.4300 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
pka2.28(at 25℃)
form Crystalline Powder
color White to off-white
optical activity[α]25/D +27°, c = 1 in H2O
Water Solubility soluble
BRN 81094
InChIKeyHXEACLLIILLPRG-RXMQYKEDSA-N
CAS DataBase Reference1723-00-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
HS Code 29333990
MSDS Information
ProviderLanguage
D(+)-Pipecolinic acid English
SigmaAldrich English
ACROS English
ALFA English
D(+)-Pipecolinic acid Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
UsesPipecolic acid is involved in synaptic transmission in the central nervous system.
Purification MethodsD-Pipecolinic acid recrystallises as platelets from EtOH and is soluble in H2O. The hydrochloride has m 256-257o(dec) from H2O and [] D25 +10.8o (c 2, H2O). [cf p 422, Lukés et al. Collect Czech Chem Commun 22 286 1957, Bayerman Recl Trav Chim Pays-Bas 78 134 1959, Asher et al. Tetrahedron Lett 22 141 1981, Beilstein 22/1 V 220.]
D(+)-Pipecolinic acid Preparation Products And Raw materials
Preparation Products(2R)-1-methyl-2-Piperidinecarboxylic acid-->(R)-1-N-BOC-2-HYDROXYMETHYLPIPERIDINE

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