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| Paeoniflorin Basic information |
| Product Name: | Paeoniflorin | | Synonyms: | 5beta-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1h-3,4-dioxacyclobuta[cd]pentalen-1alpha(2h)-yl-beta-d-glucopyranoside;PAEONIFLORIN;5-alpha,5a-alpha,5b-alpha))-a-alph;5-methano-1h-3,4-dioxacyclobuta(cd)pentalen-1a(2h)-yl,(1ar-(1a-alpha,2-beta,3;Paeoniflorin, 98%, from Paeonia sterniana Fletcher in Journ.;Paeoniflorin 23180-57-6;eoniflorin;Paeoniflorin, ≥98%(HPLC) | | CAS: | 23180-57-6 | | MF: | C23H28O11 | | MW: | 480.47 | | EINECS: | 245-476-2 | | Product Categories: | Heterocycles;Natural Plant Extract;The group of Paeoniflorin;API's;Steroids;Veterinaries;reference substance;Plant extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors | | Mol File: | 23180-57-6.mol |
| Paeoniflorin Chemical Properties |
| Melting point | approximate 124℃ (dec.) | | Boiling point | 498.51°C (rough estimate) | | density | 1.3044 (rough estimate) | | refractive index | 1.5376 (estimate) | | storage temp. | 2-8°C | | solubility | Methanol (Slightly, Sonicated), Pyridine (Slightly) | | pka | 11.52±0.70(Predicted) | | form | powder | | color | white | | InChIKey | YKRGDOXKVOZESV-WRJNSLSBSA-N | | CAS DataBase Reference | 23180-57-6(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | RT1200000 | | HS Code | 29389090 | | Toxicity | LD50 ipr-mus: 9530 mg/kg YKKZAJ 89,879,69 |
| Paeoniflorin Usage And Synthesis |
| Chemical Properties | White powder | | Uses | antiinflammatory, antispasmodic, antihypertensive, antidiuretic | | Uses | Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin has broad pharmacological effects, such as analgesic, anti-diuretic，anti-inflammatory，anti-convulsant, vasodilatic, and etc. In a study, paeoniflorin effe | | Uses | Paeoniflorin is an active compound of the Paeonia root. Paeoniflorin inhibits Aβ25-35-induced mitochondrial dysfunction, which includes decreased mitochondrial membrane potential, increased Bax/Bcl-2 ratio, cytochrome c release and activity of caspase-3 and caspase-9. Paeoniflorin could attenuate or restore the viability loss, apoptotic increase, and ROS production induced by Aβ25-35 in SH-SY5Y cells. | | General Description | Paeoniflorin has been demonstrated to exert anti-inflammatory and immunomodulatory effects. | | Biochem/physiol Actions | Herbal constituent of peony root. It is used in Chinese traditional medicine for its spasmolytic and pain-relieving properties. Exhibits anticoagulant, neuromuscular blocking, cognition-enhancing, immunoregulating, and antihyperglycemic effects. | | Safety Profile | Moderately toxic by intravenous route. Mildly toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fumes. |
| Paeoniflorin Preparation Products And Raw materials |
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