Dimethyl 3-hydroxyglutarate

Dimethyl 3-hydroxyglutarate
  • CAS No.:7250-55-7
Other grades of this product :
Dimethyl 3-hydroxyglutarate Basic information
Product Name:Dimethyl 3-hydroxyglutarate
Synonyms:3-hydroxyglutaric acid dimethyl ester;Dimethyl 3-hydroxypentanedioate;Pentanedioic acid, 3-hydroxy-, dimethyl ester;NISTC7250557;Glutaric acid, 3-hydroxy-, dimethyl ester;Nsc30047;Dimethyl 3-hydroxygl;3-Hydroxy-pentanedioic Acid DiMethyl Ester
CAS:7250-55-7
MF:C7H12O5
MW:176.17
EINECS:
Product Categories:C6 to C7;Carbonyl Compounds;Esters;Building Blocks;C6 to C7;Carbonyl Compounds;Aliphatics;Chemical Synthesis;Organic Building Blocks
Mol File:7250-55-7.mol
Dimethyl 3-hydroxyglutarate Chemical Properties
Boiling point 139-140 °C/8 mmHg (lit.)
density 1.192 g/mL at 25 °C (lit.)
refractive index n20/D 1.442(lit.)
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform
form Oil
pka12.60±0.20(Predicted)
color Clear colourless to Pale Yellow
BRN 1776666
InChIKeyCUPGMRSSZADEIW-UHFFFAOYSA-N
CAS DataBase Reference7250-55-7(CAS DataBase Reference)
NIST Chemistry ReferenceGlutaric acid, 3-hydroxy-, dimethyl ester(7250-55-7)
Safety Information
Safety Statements 23-24/25
WGK Germany 3
HS Code 29181990
MSDS Information
ProviderLanguage
SigmaAldrich English
Dimethyl 3-hydroxyglutarate Usage And Synthesis
Chemical PropertiesOff-White to Pale Yellow Oil
UsesDimethyl 3-hydroxyglutarate was used in the synthesis of two chiral fragments representing C1-11 and C12-25 of the polyene macrolide pimaricin.
UsesGlutaric Acid derivative
General DescriptionEnantioselective hydrolysis and ammonolysis of dimethyl-3-hydroxyglutarate has been studied using immobilized lipase B isolated from Candida antarctica.
Dimethyl 3-hydroxyglutarate Preparation Products And Raw materials
Preparation Products(3R)-3-(tert-Butyldimethylsilyl)oxypentanedioate-1-methyl monoester

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