Pregnenolone acetate

Pregnenolone acetate
  • CAS No.:1778-02-5
Other grades of this product :
Pregnenolone acetate Basic information
Product Name:Pregnenolone acetate
Synonyms:17-ACETYL-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE;3 BETA,21-DIHYDROXY-5-PREGNEN-20-ONE-3-ACETATE;3-BETA-HYDROXY-5-PREGNEN-20-ONE 3-ACETATE;3BETA-ACETOXY-5-PREGNEN-20-ONE;ACETIC ACID (3S,8S,9S,10R,13S,14S,17S)-17-ACETYL-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ESTER;ACETOXYPREGNENOLONE;5-PREGNEN-3BETA-OL-20-ONE 3-ACETATE;5-PREGNEN-3BETA-OL-20-ONE ACETATE
CAS:1778-02-5
MF:C23H34O3
MW:358.51
EINECS:217-212-6
Product Categories:Agonist;Biochemistry;Steroids;Steroids (Others)
Mol File:1778-02-5.mol
Pregnenolone acetate Chemical Properties
Melting point 149-152 °C(lit.)
alpha 22 º (c=2, C2H5OH 23 ºC)
Boiling point 430.93°C (rough estimate)
density 1.0816 (rough estimate)
refractive index 1.4700 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form Solid
color White
optical activity[α]20/D +19°, c = 1 in ethanol
Merck 14,7733
BRN 2062850
InChIKeyCRRKVZVYZQXICQ-RJJCNJEVSA-N
CAS DataBase Reference1778-02-5(CAS DataBase Reference)
NIST Chemistry Reference3Beta-acetoxypregn-5-en-20-one(1778-02-5)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 29153900
MSDS Information
ProviderLanguage
5-Pregnen-3beta-ol-20-one acetate English
SigmaAldrich English
ACROS English
Pregnenolone acetate Usage And Synthesis
Chemical Propertieswhite to light yellow crystalline powder or Crystallized (methanol).
UsesPregnenolone acetate is an intermediate in the synthesis of progesterone. It is uses as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. It acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. It has also been shown to stimulate locomotor activity and neuronal function in rats.
PreparationPregnenolone acetate can be prepared by catalytic hydrogenation (16-position double bond) of 16-Dehydropregnenolone acetate.
DefinitionPregnenolone acetate is a steroid ester. It is a pregnenolone derivative, a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.
Pregnenolone acetate Preparation Products And Raw materials
Raw materials16-Dehydropregnenolone acetate
Preparation ProductsMethyl 3-oxo-4-androstene-17beta-carboxylate

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