4-Chloro-3-fluorophenol

CAS No.：348-60-7

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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4-Chloro-3-fluorophenol Basic information

Product Name:	4-Chloro-3-fluorophenol
Synonyms:	4-Chloro-3-fluorophenol,98%;4-Chloro-3-fluorophenol 98%;3-fluoro-4-chlorophenol;4-CHLORO-3-FLUOROPHENOL;4-Chloro-3-fluorophenol >Phenol, 4-chloro-3-fluoro-;4-Chloro-3-fluorophenol ISO 9001：2015 REACH
CAS:	348-60-7
MF:	C6H4ClFO
MW:	146.55
EINECS:	609-036-7
Product Categories:	Fluorine series;Phenol&Thiophenol&Mercaptan;Chlorine Compounds;Fluorine Compounds;Phenols;Organic Building Blocks;Aromatic Phenols;Oxygen Compounds
Mol File:	348-60-7.mol

4-Chloro-3-fluorophenol Chemical Properties

Melting point	54-56 °C (lit.)
Boiling point	84 °C/44 mmHg (lit.)
density	1.3675 (estimate)
Fp	>230 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	chloroform: soluble50mg/mL, clear, colorless
pka	8.52±0.18(Predicted)
form	Liquid
color	Colorless to pale yellow, may discolor to orange during storage
BRN	3236440
CAS DataBase Reference	348-60-7(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20/21/22
Safety Statements	26-37/39-36/37/39-24/25
RIDADR	2811
WGK Germany	3
Hazard Note	Irritant
HazardClass	IRRITANT, IRRITANT-HARMFUL
HazardClass	8
HS Code	29081990

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

4-Chloro-3-fluorophenol Usage And Synthesis

Chemical Properties	White to salmon crystalline solid
Uses	4-Chloro-3-fluorophenol was used in the synthesis of 4-chloro-3-fluoro catechol.
General Description	4-Chloro-3-fluorophenol is hydroxylated at both ortho positions to yield different products.

4-Chloro-3-fluorophenol Preparation Products And Raw materials

Preparation Products

S-23

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