N'-Nitro-L-arginine

CAS No.：2149-70-4

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N'-Nitro-L-arginine Basic information

Product Name:	N'-Nitro-L-arginine
Synonyms:	(+)-nc-nitroarginine;H-Arg(NO₂)-OH;N_ω-Nitro-L-arginine;N⁵-(Nitroamidino)-L-2,5-diaminopentanoic acid;N^G-NO₂-L-Arg;L-NNA;L-NO2ARG;L-NOARG
CAS:	2149-70-4
MF:	C6H13N5O4
MW:	219.2
EINECS:	218-418-9
Product Categories:	Arginine [Arg, R];Amino Acids and Derivatives;Amino Acids Derivatives;Amino Acids;Nitric Oxide
Mol File:	2149-70-4.mol

N'-Nitro-L-arginine Chemical Properties

Melting point	257 °C (dec.)(lit.)
alpha	23.5 º (c=4, 2N HCl 24 ºC)
Boiling point	360°C (rough estimate)
density	1.4177 (rough estimate)
refractive index	1.8000 (estimate)
RTECS	RM2982100
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	2.49±0.24(Predicted)
form	powder to crystal
color	White to Almost white
BRN	1728914
InChIKey	MRAUNPAHJZDYCK-BYPYZUCNSA-N
CAS DataBase Reference	2149-70-4(CAS DataBase Reference)
EPA Substance Registry System	L-Ornithine, N5-[imino(nitroamino)methyl]- (2149-70-4)

Safety Information

Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	22-24/25-36-26
WGK Germany	3
TSCA	Yes
HazardClass	IRRITANT
HS Code	29299090

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

N'-Nitro-L-arginine Usage And Synthesis

Chemical Properties	WHITE TO OFF-WHITE POWDER
Uses	Nω-Nitro-L-arginine is an inhibitor for nitric oxide synthase and is used in the study of bacterium to determine effective treatments. Used in the study of MRSA (Methicillin-Resistant Staphylococcus Aureus).
Hazard	A reproductive hazard.
Biological Activity	NO synthase inhibitor.
Biochem/physiol Actions	Nω-Nitro-L-arginine/L-NNA helps to reduce the levels of cortical hyperemia and brain cGMP occurring due to hypercapnia.
Safety Profile	Experimental reproductiveeffects. When heated to decomposition it emits toxicvapors of NOx.

N'-Nitro-L-arginine Preparation Products And Raw materials

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