CREATINE AMIDINOHYDROLASE

CREATINE AMIDINOHYDROLASE
  • CAS No.:37340-58-2

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
CREATINE AMIDINOHYDROLASE Basic information
Product Name:CREATINE AMIDINOHYDROLASE
Synonyms:creatinase from actinobacillus species;creatinase from flavobacterium sp.;creatinase from pseudomonas species:*recombinant;CREATINASE FROM FLAVOBACTERIUM SPECIES;CREATINASE FROM FLAVOBACTERIUM SP., LYOP HIL., ~10 U/MG;creatinase from actinobacillus sp.;creatinase from pseudomonas sp.;EC 3.5.3.3
CAS:37340-58-2
MF:
MW:0
EINECS:253-471-1
Product Categories:
Mol File:Mol File
CREATINE AMIDINOHYDROLASE Chemical Properties
storage temp. 2-8°C
form lyophilized powder
color white
EPA Substance Registry SystemCreatinase (37340-58-2)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
F 10-21
MSDS Information
ProviderLanguage
SigmaAldrich English
CREATINE AMIDINOHYDROLASE Usage And Synthesis
UsesCreatine amidinohydrolase is a clinically important enzyme used in the determination of creatinine in blood and urine.
General DescriptionCreatinase is a homodimer that catalyzes hydrolysis of creatine. It consists of two monomer subunit and two defined domains; N and C terminal domains. C terminal fold have both the α helices and anti-parallel β sheet within two structurally similar domains.In between these two domains, there is a sulfhydryl group that acts as active site and the activity is metal independent.
Biochem/physiol ActionsCreatinase is a homodimer with subunit molecular weights of approximately 45 kDa. It catalyzes the hydrolysis of creatine, in the presence of H2O, to form urea and sarcosine.
CREATINE AMIDINOHYDROLASE Preparation Products And Raw materials

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