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| Sertaconazole nitrate Basic information |
| Sertaconazole nitrate Chemical Properties |
| Melting point | 158-160° | | storage temp. | -20°C | | solubility | DMSO: soluble20mg/mL, clear | | form | powder | | pka | pKb: 7.26(at 25℃) | | color | white to beige | | InChIKey | HAAITRDZHUANGT-UHFFFAOYSA-N |
| Sertaconazole nitrate Usage And Synthesis |
| Description | Sertaconazole nitrate is a new broad spectrum imidazole antifungal agent introduced in
a topical formulation for the treatment of cutaneous infections. Its mechanism of action
is the inhibition of ergosterol synthesis and interference with the permeability of fungus
cell membranes. An oral formulation is currently under investigation for the treatment
of bucco-pharyngeal fungal infections. | | Chemical Properties | Off-White Solid | | Originator | Ferrer (Spain) | | Uses | An imidazole antifungal agent, inhibits the synthesis of ergosterol, an essential cell wall component of fungi. | | Uses | Antibacterial;ergosterol synthesis inhibitor | | Brand name | Dermofix; Zalain |
| Sertaconazole nitrate Preparation Products And Raw materials |
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