Other grades of this product :
| Product Name: | HA14-1 | | Synonyms: | 2-Amino-6-bromo-alpha-cyano-3-(ethoxycarbonyl)-(4H)-1-benzopyrane-4-aceticacidethylester;ethyl 6-broMo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chroMene-3-carboxylate;2-Amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester, Ethyl [2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)]-4H-chromene-3-carboxylate;[Ethyl 2-amino-6-bromo-4-(1cyano-2-ethoxy-2-oxoethyl)-4H-chromene3-3carboxylate], Ethyl [2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)]-4H-chromene-3-carboxylate;2-Amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-aceticacidethylester;2-Amino-6-bromo-alpha-cyano-3-(ethoxycarbonyl)-(alphaR,4R)-rel-4H-1-benzopyran-4-acetic acid ethyl ester;Ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-1-benzopyran-3-carboxylate;CS-392 | | CAS: | 65673-63-4 | | MF: | C17H17BrN2O5 | | MW: | 409.23 | | EINECS: | | Product Categories: | Inhibitors;Caspases/Apoptosis;Inhibitor | | Mol File: | 65673-63-4.mol |
| HA14-1 Chemical Properties |
| Melting point | 105 °C | | density | 1.480 | | storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C | | solubility | DMSO: 26 mg/mL | | form | powder | | CAS DataBase Reference | 65673-63-4 |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | HS Code | 29322090 |
| HA14-1 Usage And Synthesis |
| Uses | HA14-1 is a cell-permeable, nonpeptidic Bcl-2 inhibitor. | | Biological Activity | Cell-permeable inhibitor of Bcl-2 protein (IC 50 ~ 9 μ M); acts by binding to the surface pocket. Disrupts Bax/Bcl-2 interaction and induces apoptosis of tumor cells. | | Biochem/physiol Actions | HA 14-1 is a nonpeptide apoptosis inducer; Bcl-2 antagonist. |
| HA14-1 Preparation Products And Raw materials |
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