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| Ethyl bromodifluoroacetate Basic information |
| Ethyl bromodifluoroacetate Chemical Properties |
| Boiling point | 112 °C/700 mmHg (lit.) | | density | 1.583 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.387(lit.) | | Fp | 70 °F | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Soluble in most organic solvents. | | form | Liquid | | color | Clear colorless to slightly yellow | | Specific Gravity | 1.583 | | BRN | 1906095 | | InChIKey | IRSJDVYTJUCXRV-UHFFFAOYSA-N | | CAS DataBase Reference | 667-27-6(CAS DataBase Reference) | | NIST Chemistry Reference | Ethyl bromodifluoroacetate(667-27-6) |
| Hazard Codes | C,F,Xi | | Risk Statements | 10-34-36 | | Safety Statements | 26-36/37/39-45-16-27 | | RIDADR | UN 2924 3/PG 2 | | WGK Germany | 3 | | Hazard Note | Irritant/Flammable | | TSCA | No | | HazardClass | 3 | | PackingGroup | II | | HS Code | 29159000 |
| Ethyl bromodifluoroacetate Usage And Synthesis |
| Chemical Properties | clear colorless to slightly yellow liquid | | Uses | Ethyl bromodifluoroacetate is usually used in the preparation of substituted ethyl 2′-pyridyldifluoroacetates,4-alkoxymethyl- and 4-aryloxymethyl-3,3-difluoropiperidines,α,α-difluoro-β-lactams,mono- and difluoromethylated phenanthridine derivatives.
| | Uses | Efficient difluoroalkylation of aryl boronic acids via palladium catalysis. Novel, moisture-stable bromodifluoromethylated phosphonate, ester, and amide. Efficient coupling with aryl boronic acids via Pd catalysis. | | Uses | Ethyl bromodifluoroacetate, is used for the treatment of the Reformat sky reagent with aldehydes and ketones affords 2,2-difluoro-3-hydroxy esters. It is also used in the analysis of reagent purity through IR, NMR. |
| Ethyl bromodifluoroacetate Preparation Products And Raw materials |
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