1-Boc-3-(cyanomethylene)azetidine

1-Boc-3-(cyanomethylene)azetidine
  • CAS No.:1153949-11-1
Other grades of this product :
1-Boc-3-(cyanomethylene)azetidine Basic information
Uses
Product Name:1-Boc-3-(cyanomethylene)azetidine
Synonyms:1-Boc-3-(cyanomethylene)azetidine;3-Cyanomethylene-azetidine-1-carboxylic acid tert-butyl ester;tert-butyl 3-(cyanoMethylene)azetidine-1-carboxylate;tert-butyl 3-(cyanoMethylidene)azetidine-1-carboxylate;3-(Cyanomethylene)-1-azetidinecarboxylic acid tert-butyl ester;1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine;P-Hydroxy phenyl butanone (Raspberry ketone);tert-Butyl 3-(cyanomethylene)
CAS:1153949-11-1
MF:C10H14N2O2
MW:194.23
EINECS:
Product Categories:
Mol File:1153949-11-1.mol
1-Boc-3-(cyanomethylene)azetidine Chemical Properties
Boiling point 309.7±35.0 °C(Predicted)
density 1.215
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka-1.88±0.20(Predicted)
form powder to crystal
color White to Orange to Green
Safety Information
RIDADR UN 3439 6.1/PG III
HazardClass 6.1
PackingGroup III
HS Code 2933998090
MSDS Information
1-Boc-3-(cyanomethylene)azetidine Usage And Synthesis
Uses1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine is used in the synthesis of baricitinib via Horner-Emmons reaction of tert-butyl-oxoazetidine-carboxylate followed by sulfonamidation, nucleophilic addition. and subsequent Suzuki-coupling reaction.
Uses1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine is used in the synthesis of baricitinib via Horner-Emmons reaction of tert-butyl-oxoazetidine-carboxylate followed by sulfonamidation, nucleophilic addition. and subsequent Suzuki-coupling reaction.
1-Boc-3-(cyanomethylene)azetidine Preparation Products And Raw materials

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