![1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-indole-7-carbonitrile](/img/350797-56-7.jpg "1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-indole-7-carbonitrile")
| 1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-indole-7-carbonitrile Basic information |
| Product Name: | 1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-indole-7-carbonitrile |
| Synonyms: | 3-(7-Cyano-5-(2-nitropropyl)indolin-1-yl)propyl benzoate;SL-5;1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-indole-7-carbonitrile;3-[7-cyano-5-(2-nitropropyl)-2,3-dihydroindol-1-yl]propyl benzoate;Silodosin Nitro Impurity;1H-Indole-7-carbonitrile, 1-[3-(benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-;1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-in...;350797-56-7 |
| CAS: | 350797-56-7 |
| MF: | C22H23N3O4 |
| MW: | 393.44 |
| EINECS: | 1592732-453-0 |
| Product Categories: | |
| Mol File: | 350797-56-7.mol |
| 1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-indole-7-carbonitrile Chemical Properties |
| Melting point | 73-75°C |
| Boiling point | 608.6±55.0 °C(Predicted) |
| density | 1.27 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 7.80±0.13(Predicted) |
| form | Solid |
| color | Light Yellow to Yellow |
| Safety Information |
| MSDS Information |
| 1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-indole-7-carbonitrile Usage And Synthesis |
| Uses | 3-(7-Cyano-5-(2-nitropropyl)indolin-1-yl)propyl Benzoate is used in the preparation of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy. |
| 1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-indole-7-carbonitrile Preparation Products And Raw materials |
| Preparation Products | 5-(2-Aminopropyl)-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile-->Silodosin |
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