2,4-Difluorophenol

2,4-Difluorophenol
  • CAS No.:367-27-1
Other grades of this product :
2,4-Difluorophenol Basic information
Product Name:2,4-Difluorophenol
Synonyms:2,4-Difluorophenol 98%;4-Difluorophenol;2,4- twodifluoro phenol;2,4-Difluorophenol 98%, 4-Difluorophenol 98%;2,4-DIFLUOROPHENOL;Phenol, 2,4-difluoro-;2,4-Difluorophenol, 98+%;2,4-Difluorophenol, 99+%
CAS:367-27-1
MF:C6H4F2O
MW:130.09
EINECS:206-688-0
Product Categories:Organic Building Blocks;Oxygen Compounds;Fluoro-Aromatics;Aromatic Phenols;Fluorobenzene;Phenols;Phenol&Thiophenol&Mercaptan;Fluorophenols;Heterocyclic Acids,Quinolines
Mol File:367-27-1.mol
2,4-Difluorophenol Chemical Properties
Melting point 22.4 °C (lit.)
Boiling point 52-53 °C/19 mmHg (lit.)
density 1.362 g/mL at 25 °C (lit.)
refractive index n20/D 1.486(lit.)
Fp 134 °F
storage temp. Inert atmosphere,Room Temperature
pka8.72±0.18(Predicted)
form powder to lump to clear liquid
color White or Colorless to Yellow
Specific Gravity1.362
Water Solubility slightly soluble
BRN 1934803
InChIKeyNVWVWEWVLBKPSM-UHFFFAOYSA-N
CAS DataBase Reference367-27-1(CAS DataBase Reference)
NIST Chemistry Reference2,4-Difluorophenol(367-27-1)
Safety Information
Hazard Codes Xn,Xi,C,F
Risk Statements 20/21/22-37/38-41-34-11-36/37/38
Safety Statements 26-36/37/39-45-16
RIDADR 1992
WGK Germany 3
Hazard Note Harmful
HazardClass 3
PackingGroup III
HS Code 29081000
MSDS Information
ProviderLanguage
2,4-Difluorophenol English
SigmaAldrich English
ACROS English
ALFA English
2,4-Difluorophenol Usage And Synthesis
Chemical Propertiesclear yellow-green liquid after melting
Uses2,4-Difluorophenol, is an organic building block used for the synthesis of various pharmaceutical compounds, such as antivirulence agents. It is also used in the synthesis of new α-Phenoxyacetamide derivatives, acting as type III secretion system of Pseudomonas aeruginosa PAO1, a gram-negative bacteria.
Uses2,4-Difluorophenol has been used:
  • as starting reagent during the synthesis of 4,6-difluoro-5,7-dihydroxytryptamine
  • in the synthesis of 3-carboxy-6,8-difluoro-7-hydroxycoumarin (Pacific Blue), fluorinated fluorescent dye

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