| QUINOLINE-4-CARBOXYLIC ACID Basic information |
| Product Name: | QUINOLINE-4-CARBOXYLIC ACID |
| Synonyms: | Quinoline-4-carboxylic acid ,97%;quinoline-4-carboxylic acid(SALTDATA: FREE);Quinoline-4-carboxylic;Cinchoninic acid (6CI,7CI,8CI);NSC 13138;4-Quinolinecarboxylic acid, 98%+;4-Quinolinecarboxylic acid 97%;Cinchonic acid |
| CAS: | 486-74-8 |
| MF: | C10H7NO2 |
| MW: | 173.17 |
| EINECS: | 207-640-1 |
| Product Categories: | Quinolinecarboxylic Acids, etc.;Quinolines;Carboxylic Acids;Quinolines, Isoquinolines & Quinoxalines;Building Blocks;Heterocyclic Building Blocks;Quinolines, Quinazolines and derivatives;pharmacetical;Carboxylic Acids;Quinolines, Isoquinolines & Quinoxalines;Quinoline&Isoquinoline;Quinoline Derivertives |
| Mol File: | 486-74-8.mol |
| QUINOLINE-4-CARBOXYLIC ACID Chemical Properties |
| Melting point | 254-255 °C (lit.) |
| Boiling point | 348.7±15.0 °C(Predicted) |
| density | 1.339±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | powder to crystal |
| pka | 1.03±0.10(Predicted) |
| color | White to Light yellow |
| BRN | 5224 |
| CAS DataBase Reference | 486-74-8(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-36/38 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 3 |
| RTECS | GD3850000 |
| HazardClass | IRRITANT |
| HS Code | 29334900 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ALFA | English |
| QUINOLINE-4-CARBOXYLIC ACID Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder |
| Uses | Quinoline-4-carboxylic Acid for small therapeutic agent compounds. |
| Biochem/physiol Actions | 4-Quinolinecarboxylic acid showed anti-tumor activity against L1210 leukemia and B16 melanoma. |
| Metabolic pathway | The bacterium which is isolated from soil enrichment culture degrades quinoline-4-carboxylic acid to give the two identified metabolites 2-oxo-1,2- dihydroquinoline-4-carboxylic acid and 8-hydroxy-2- oxo-2H-benzopyran-4-carboxylic acid. |
| QUINOLINE-4-CARBOXYLIC ACID Preparation Products And Raw materials |
| Raw materials | Ethyl acetate-->Diethyl ether-->Sulfuric acid-->N,N-Dimethylformamide-->PETROLEUM ETHER-->Sodium carbonate-->n-Butyllithium-->Hydrogen peroxide-->Nitrogen-->1,4-Dioxane-->Triethyl orthoformate-->Aniline-->Formic acid-->Phosphorus tribromide-->Diphenyl ether-->Selenium dioxide-->Lepidine-->2,2-Dimethyl-1,3-dioxane-4,6-dione-->Selenious acid |
| Preparation Products | 8-NITROQUINOLINE-4-CARBOXYLIC ACID |
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