5,7-Dimethoxycoumarin

5,7-Dimethoxycoumarin
  • CAS No.:487-06-9
Other grades of this product :
5,7-Dimethoxycoumarin Basic information
Product Name:5,7-Dimethoxycoumarin
Synonyms:2H-1-Benzopyran-2-one, 5,7-dimethoxy-;5,7-dimethoxy-2h-1-benzopyran-2-on;5,7-Dimethoxy-2H-chromen-2-one;5,7-dimethoxy-1-benzopyran-2-one;NSC 102793;NSC 217987;5,7-dimethoxy-coumari;5,7-dimethyloxy-2H-1-benzopyran-2-one
CAS:487-06-9
MF:C11H10O4
MW:206.19
EINECS:207-646-4
Product Categories:Inhibitors;API intermediates;Coumarins
Mol File:487-06-9.mol
5,7-Dimethoxycoumarin Chemical Properties
Melting point 146-149 °C (lit.)
Boiling point 305.04°C (rough estimate)
density 1.2607 (rough estimate)
refractive index 1.4570 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Acetonitrile (Slightly), Chloroform (Slightly)
form Solid
color White to Off-White
Merck 14,5492
CAS DataBase Reference487-06-9(CAS DataBase Reference)
NIST Chemistry Reference2H-1-benzopyran-2-one, 5,7-dimethoxy-(487-06-9)
EPA Substance Registry System2H-1-Benzopyran-2-one, 5,7-dimethoxy- (487-06-9)
Safety Information
Hazard Codes Xi
Risk Statements 43
Safety Statements 36/37
WGK Germany 3
RTECS GN6530000
HS Code 2932209090
MSDS Information
ProviderLanguage
5,7-Dimethoxychromen-2-one English
SigmaAldrich English
ALFA English
5,7-Dimethoxycoumarin Usage And Synthesis
Usesphotosensitizing agent
Uses5,7-Dimethoxycoumarin is a derivitized coumarin compound.
Synthesis Reference(s)Journal of the American Chemical Society, 118, p. 6305, 1996 DOI: 10.1021/ja961107i
General Description5,7-dimethoxycoumarin is isolated and identified from leaves and fruits of Pelea anisata H. Mann, a plant whose fruit are used in the construction of mohikana leis. It induces frameshift mutagenesis in bacteria. It also causes lethal photosensitization and the formation of sister chromatid exchanges in Chinese hamster cells.
Biochem/physiol Actions5,7-Dimethoxycoumarin induces the processes of differentiation and melanogenesis in murine (B16) and human (A375).

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