(-)-Corey lactone diol

(-)-Corey lactone diol
  • CAS No.:32233-40-2
Other grades of this product :
(-)-Corey lactone diol Basic information
Product Name:(-)-Corey lactone diol
Synonyms:(-) COREY LACTONE DIOL;(-)-COREY LACTONE DIOL,98%;(3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE,;(1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone;(1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one;(3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one;(-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one,98%;(+)-6β-Hydroxymethyl-7α-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one
CAS:32233-40-2
MF:C8H12O4
MW:172.18
EINECS:608-721-8
Product Categories:Latanoprost;Prostaglandins;API
Mol File:32233-40-2.mol
(-)-Corey lactone diol Chemical Properties
Melting point 117-119 °C(lit.)
Boiling point 262.49°C (rough estimate)
density 1.2104 (rough estimate)
refractive index 1.4455 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka14.36±0.40(Predicted)
form Crystalline Powder or Crystals
color White to beige-brown
optical activity[α]20/D 44°, c = 1.4 in methanol
InChIKeyVYTZWRCSPHQSFX-GBNDHIKLSA-N
CAS DataBase Reference32233-40-2(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29322090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
(-)-Corey lactone diol Usage And Synthesis
Chemical Propertieswhite to beige-brown cryst. powder or crystals
Uses(-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmo nary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
Uses(-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud''s phenomenon and ischemia.

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