2-Chloro-N,N-dimethylacetamide

CAS No.：2675-89-0

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2-Chloro-N,N-dimethylacetamide Basic information

Product Name:	2-Chloro-N,N-dimethylacetamide
Synonyms:	N,N-DIMETHYL-2-CHLOROACETAMIDE;N,N-DIMETHYLCHLOROACETAMIDE;N,N-DIMETHYLCHOROACETAMIDE;CHLOROACETYLDIMETHYLAMINE;AKOS BBS-00000943;2-CHLORO-N,N-DIMETHYLACETAMIDE;2-chloro-N,N-dimethyl-ethanamide;2-Chloro-N,N-dimethylacetacetamide
CAS:	2675-89-0
MF:	C4H8ClNO
MW:	121.57
EINECS:	220-224-4
Product Categories:
Mol File:	2675-89-0.mol

2-Chloro-N,N-dimethylacetamide Chemical Properties

Melting point	15-16 °C
Boiling point	98-100°C/11mm
density	1.182 g/mL at 20 °C (lit.)
refractive index	n20/D 1.479
Fp	98-100°C/11mm
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly), Hexane (Slightly), Methanol (Slightly)
pka	-0.95±0.70(Predicted)
form	Liquid
color	Clear colorless to pale yellow
BRN	969568
InChIKey	XBPPLECAZBTMMK-UHFFFAOYSA-N
CAS DataBase Reference	2675-89-0(CAS DataBase Reference)

Safety Information

Hazard Codes	C
Risk Statements	22-34
Safety Statements	26-36/37/39-45
RIDADR	UN 3265 8/PG 3
WGK Germany	3
HS Code	29241990

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

2-Chloro-N,N-dimethylacetamide Usage And Synthesis

Uses	2-Chloro-N,N-dimethylacetamide is N,M-dialkyl amide used as an organic catalyst in the preparation of phosphorylated thiosemicarbazide.
Uses	2-Chloro-N,N-dimethylacetamide (N,N-dimethylchloroacetamide) was used in the synthesis of (S)-carbinoxamine.

2-Chloro-N,N-dimethylacetamide Preparation Products And Raw materials

Raw materials	Sodium hydroxide-->Dichloromethane-->Sodium bicarbonate-->Dimethylamine-->Chloroacetyl chloride-->Dimethylamine hydrochloride
Preparation Products	N-ME-GLY-NME2-->2-Chloro-N-phenylacetamide

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