| 4-Methylumbelliferyl-beta-D-glucuronide Basic information |
| Product Name: | 4-Methylumbelliferyl-beta-D-glucuronide |
| Synonyms: | 4-METHYL-2-OXO-2H-1-BENZOPYRAN-7-YL, BETA-D-GLUCO-PYRANOSIDURONIC ACID;4-METHYLUMBELLIFERYL B-D-GLUCURONIDE;4-METHYLUMBELLIFERYL-BETA-D-GLUCURONIC ACID;4-METHYLUMBELLIFERYL-BETA-D-GLUCURONIDE;MUG;MUGLCU;4-Methylumbelliferyl-b-D-glucuronide hydrate;4-methylumberiferryl-beta-D-glucuronide trihydrate |
| CAS: | 6160-80-1 |
| MF: | C16H16O9 |
| MW: | 352.3 |
| EINECS: | 228-186-0 |
| Product Categories: | Substrates;substrate;Fluorescent Labels & Indicators;Glucuronides |
| Mol File: | 6160-80-1.mol |
| 4-Methylumbelliferyl-beta-D-glucuronide Chemical Properties |
| Melting point | 102 °C |
| alpha | -105 º (c=0.25, water 30 ºC) |
| Boiling point | 683.1±55.0 °C(Predicted) |
| density | 1.632±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | Methanol (Slightly), Water (Slightly) |
| pka | 2.76±0.70(Predicted) |
| form | White crystalline solid |
| color | White |
| Water Solubility | slightly soluble |
| Sensitive | Moisture Sensitive |
| InChIKey | ARQXEQLMMNGFDU-YXNYVWNSSA-N |
| CAS DataBase Reference | 6160-80-1(CAS DataBase Reference) |
| EPA Substance Registry System | .beta.-D-Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl (6160-80-1) |
| Safety Information |
| Hazard Codes | Xi,Xn |
| Risk Statements | 22-40 |
| Safety Statements | 24/25-36/37 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29329990 |
| MSDS Information |
| Provider | Language |
|---|---|
| 4-Methylumbelliferyl-beta-D-glucuronide | English |
| ALFA | English |
| 4-Methylumbelliferyl-beta-D-glucuronide Usage And Synthesis |
| Description | 4-Methylumbelliferyl-beta-D-glucuronide is a fluorescent substrate of β-glucuronidase. Once cleaved, 4-Methylumbelliferyl-beta-D-glucuronide yields blue fluorescence seen under UV light which is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively. It is ideal for working with Escherichia coli and plant molecular studies. |
| Chemical Properties | Crystalline |
| Uses | 4-Methylumbelliferyl-beta-D-glucuronide is a substrate for glucuronidase. Also used as a test for coliform bacteria in water. Fluorescence: max. Abs. 316nm; max. Em. 375nm; e x 10-3: 12 |
| Uses | Substrate for ?-D-glucuronidase assay. MUG is widely used as component of selective microbial culture media. |
| Uses | 4-Methylumbelliferyl β-D-glucuronide dihydrate is a useful building block and a fluorophore. |
| Definition | ChEBI: A beta-D-glucosiduronic acid having a 4-methylumbelliferyl substituent at the anomeric position. |
| 4-Methylumbelliferyl-beta-D-glucuronide Preparation Products And Raw materials |
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