2-Amino-4-chloro-6-methylpyrimidine

CAS No.：5600-21-5

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2-Amino-4-chloro-6-methylpyrimidine Basic information

Product Name:	2-Amino-4-chloro-6-methylpyrimidine
Synonyms:	TIMTEC-BB SBB004134;2-amino-4-chloro-6-methyl-pyrimidin;2-Pyrimidinamine, 4-chloro-6-methyl-;2-AMINO-4-CHLORO-6-METHYLPYRIMIDINE (ACLP);2-Amino-4-chloro-6-methylpyrimidine ,97%;4-Chloro-6-methyl-pyrimidine-2-amine;2-Amino-4-chloro-6-methylpyrimidine,98%;AMR human cell line
CAS:	5600-21-5
MF:	C5H6ClN3
MW:	143.57
EINECS:	227-018-3
Product Categories:	PYRIMIDINE;Heterocycle-Pyrimidine series;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;FINE Chemical & INTERMEDIATES;Fluorobenzene;Amines;Pyrazines, Pyrimidines & Pyridazines;Pyrimidines;PyrimidinesHeterocyclic Building Blocks;Building Blocks;C4 to C5;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks
Mol File:	5600-21-5.mol

2-Amino-4-chloro-6-methylpyrimidine Chemical Properties

Melting point	183-186 °C (lit.)
Boiling point	234.32°C (rough estimate)
density	1.2986 (rough estimate)
refractive index	1.6000 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	acetic acid: soluble50mg/mL, clear, colorless to faintly yellow
pka	4.26±0.10(Predicted)
form	Solid
color	White to Off-White
Water Solubility	Insoluble in water.
BRN	114297
CAS DataBase Reference	5600-21-5(CAS DataBase Reference)
NIST Chemistry Reference	2-Amino-4-chloro-6-methylpyrimidine(5600-21-5)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20/21/22
Safety Statements	22-24/25-37/39-26-36
WGK Germany	3
RTECS	UV6329600
HazardClass	IRRITANT, AVOID SKIN CONTACT
HS Code	29335995

MSDS Information

Provider	Language
2-Amino-4-chloro-6-methylpyrimidine	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Amino-4-chloro-6-methylpyrimidine Usage And Synthesis

Chemical Properties	WHITE TO LIGHT YELLOW NEEDLE-LIKE CRYST. POWDER
Uses	2-Amino-4-chloro-6-methylpyrimidine was used to study the influence of chlorine substitution in pyrimidine ring on proton donor ability of amino group in 2-aminopyrimidine.
Definition	ChEBI: An aminopyrimidine compound having its amino group at position 2 and chloro and methyl substituents at positions 4 and 6 respectively.
General Description	2-Amino-4-chloro-6-methylpyrimidine is a nitification inhibitor.
Purification Methods	Recrystallise it from EtOH. [Beilstein 24 H 84.]

2-Amino-4-chloro-6-methylpyrimidine Preparation Products And Raw materials

Raw materials	Diethyl ether-->Sodium-->Phosphorus oxychloride-->Ethyl acetoacetate-->Guanidine hydrochloride-->4-Chloro-2-ethylsulfanyl-6-methyl-pyrimidine-->2-Amino-6-methyl-4-pyrimidinol-->2-Chloro-6-methylpyrimidin-4-ylamine-->2,4-Dichloro-6-methylpyrimidine
Preparation Products	SGI-1027-->2-Amino-4,6-dimethylpyrimidine

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