4-Bromoquinoline

CAS No.：3964-04-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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4-Bromoquinoline Basic information

Product Name:	4-Bromoquinoline
Synonyms:	4-BROMOQUINOLINE;4-Bromopuinoline;4-BROMOQUINOLINE,97%;4-Bromoquinoline 3964-4-3;4-BromoquinoL;Quinoline, 4-bromo-;4-Bromoquinoline ,98%;4-BroMoquinoline, 95+%
CAS:	3964-04-3
MF:	C9H6BrN
MW:	208.05
EINECS:	625-847-9
Product Categories:	Organohalides;Quinoline;Quinoline Derivertives;Quinolines, Isoquinolines & Quinoxalines;Building Blocks;Halogenated Heterocycles;Halides;Quinolines, Isoquinolines & Quinoxalines;Quinoline&Isoquinoline;Heterocyclic Building Blocks;Quinolines;QuinolinesHeterocyclic Building Blocks
Mol File:	3964-04-3.mol

4-Bromoquinoline Chemical Properties

Melting point	29-34 °C
Boiling point	270 C
density	1.564±0.06 g/cm3(Predicted)
Fp	>110℃
storage temp.	2-8°C
pka	3.39±0.13(Predicted)
CAS DataBase Reference	3964-04-3(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20/21/22
Safety Statements	26-36
WGK Germany	3
Hazard Note	Irritant
HS Code	29334900

MSDS Information

4-Bromoquinoline Usage And Synthesis

Chemical Properties	Light yellow solid
Uses	4-Bromoquinoline is used to prepare bone morphogenetic protein (BMP) signaling inhibitors. It is also used to synthesize novel azalides derived from 16-membered macrolides.
Synthesis Reference(s)	The Journal of Organic Chemistry, 72, p. 2232, 2007 DOI: 10.1021/jo062168u

4-Bromoquinoline Preparation Products And Raw materials

Raw materials	Ethyl acetate-->Diethyl ether-->Sulfuric acid-->Acetic acid-->N,N-Dimethylformamide-->PETROLEUM ETHER-->Nitric acid-->Chloroform-->Hydrogen peroxide-->Triethyl orthoformate-->Aniline-->Phosphorus tribromide-->Diphenyl ether-->Quinoline-->2,2-Dimethyl-1,3-dioxane-4,6-dione-->4-bromoquinoline N-oxide
Preparation Products	4-Methoxyquinoline-->4-NITROQUINOLINE

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