1-(4-Fluorophenyl)piperazine

CAS No.：2252-63-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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1-(4-Fluorophenyl)piperazine Basic information

Product Name:	1-(4-Fluorophenyl)piperazine
Synonyms:	FLUOROPHENYL PIPERAZINE;TRIFLUOROETHOXY FLUOROPHENYL PIPERAZINE;1-(4-Fluorophenyl)piperazine, 98% 10GR;4-(1-Piperazino)fluorobenzene;1-(4-Fluorophenyl)piperazine 97%;1-(4-Fluorophenyl)piperazine97%;1-(4-Fluorophenyl)piperazine ,98%;4-(4-Fluorophenyl)piperazine
CAS:	2252-63-3
MF:	C10H13FN2
MW:	180.22
EINECS:	218-846-6
Product Categories:	Nitrogen cyclic compounds;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Piperidines, Piperidones, Piperazines;Piperaizine;API intermediates;Building Blocks;Heterocyclic Building Blocks;Piperazines;Bioactive Small Molecules;Building Blocks;C10;Cell Biology;Chemical Synthesis;F;Fluorinated Building Blocks;Heterocyclic Building Blocks;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles
Mol File:	2252-63-3.mol

1-(4-Fluorophenyl)piperazine Chemical Properties

Melting point	30-33 °C (lit.)
Boiling point	118-123 °C/0.1 mmHg (lit.)
density	1.0
refractive index	1.5585-1.5605
Fp	>230 °F
storage temp.	Refrigerator
form	Liquid After Melting
pka	8.93±0.10(Predicted)
color	Clear yellow
Water Solubility	Insoluble in water.
Sensitive	Air Sensitive
BRN	610723
CAS DataBase Reference	2252-63-3(CAS DataBase Reference)
NIST Chemistry Reference	1-(P-fluorophenyl)piperazine(2252-63-3)

Safety Information

Hazard Codes	Xn,T,C
Risk Statements	22-36/37/38-20/21/22
Safety Statements	26-36
RIDADR	2811
WGK Germany	2
Hazard Note	Toxic/Corrosive
HazardClass	8
PackingGroup	III
HS Code	29339900

MSDS Information

Provider	Language
1-(4-Fluorophenyl)piperazine	English
SigmaAldrich	English
ACROS	English
ALFA	English

1-(4-Fluorophenyl)piperazine Usage And Synthesis

Chemical Properties	clear yellowish liquid after melting
Uses	1-(4-Fluorophenyl)piperazine is a major metabolite of Niaparazine, a sedative, hypnotic drug. Metabolites of Niaprazine occurred by N-dealkylation, N-dearylation, aromatic hydroxylation and N-oxidatio n.
Uses	1-(4-Fluorophenyl)piperazine was used in the synthesis of N,N-disubstituted piperazine. It is a major metabolite of niaparazine, a sedative, a hypnotic drug.

1-(4-Fluorophenyl)piperazine Preparation Products And Raw materials

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