DIMETHYL PROPARGYLMALONATE

DIMETHYL PROPARGYLMALONATE
  • CAS No.:95124-07-5

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
DIMETHYL PROPARGYLMALONATE Basic information
Product Name:DIMETHYL PROPARGYLMALONATE
Synonyms:DIMETHYL PROPARGYLMALONATE;Dimethyl propargylmalonate >=95.0% (GC);Dimethyl2-(prop-2-yn-1-yl)malonate;Dimethyl proparylmalonate;dimethyl 2-prop-2-ynylpropanedioate;Dimethyl propargylmalote;dimethyl (prop-2-yn-1-yl)malonate;Propanedioic acid, 2-(2-propyn-1-yl)-, 1,3-dimethyl ester
CAS:95124-07-5
MF:C8H10O4
MW:170.16
EINECS:
Product Categories:C8 to C9;Carbonyl Compounds;Esters
Mol File:95124-07-5.mol
DIMETHYL PROPARGYLMALONATE Chemical Properties
Boiling point 93-95 °C/7 mmHg (lit.)
density 1.119 g/mL at 20 °C (lit.)
refractive index n20/D 1.444
Fp 113 °C
storage temp. Sealed in dry,Room Temperature
BRN 3539408
Safety Information
Safety Statements 23-24/25
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
DIMETHYL PROPARGYLMALONATE Usage And Synthesis
UsesDimethyl propargylmalonate can be used as a reactant to synthesize:
  • Nitro methylenecyclopentanes by [3+2] annulation reaction with various nitroalkenes in the presence of Triton B.
  • Propargylmalonamides intermediates, applicable in the preparation of ″click BOX″ ligands by copper-catalyzed cycloaddition and oxazoline ring formation reaction.
  • Cyclopentene derivatives by reacting with various α, β-unsaturated ketones using a combination of organocatalysts and transition metal catalysts.
DIMETHYL PROPARGYLMALONATE Preparation Products And Raw materials

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