Methyl L-pyroglutamate

CAS No.：4931-66-2

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Methyl L-pyroglutamate Basic information

Product Name:	Methyl L-pyroglutamate
Synonyms:	2-PYRROLIDONE-5-CARBOXYLIC ACID METHYL ESTER;METHYL L-PYROGLUTAMATE;METHYL (S)-2-PYRROLIDINONE-5-CARBOXYLATE;METHYL (S)-(+)-2-PYRROLIDONE-5-CARBOXYLATE;L-PYR-OME;(+)-L-PYROGLUTAMIC ACID METHYL ESTER;L-PYROGLUTAMIC ACID METHYL ESTER;H-PGLU-OME
CAS:	4931-66-2
MF:	C6H9NO3
MW:	143.14
EINECS:	225-567-3
Product Categories:	Chiral Reagents;Amino Acids;pharmacetical;Amino Acid Derivatives
Mol File:	4931-66-2.mol

Methyl L-pyroglutamate Chemical Properties

Boiling point	90°C (0.3 mmHg)
alpha	10.5 º (c=1, EtOH)
density	1.226
refractive index	1.486
Fp	>110°C
storage temp.	Inert atmosphere,Room Temperature
form	Liquid
pka	14.65±0.40(Predicted)
color	Pale yellow
optical activity	[α]20/D +10.5°, c = 1 in ethanol
CAS DataBase Reference	4931-66-2(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HS Code	29337900

MSDS Information

Methyl L-pyroglutamate Usage And Synthesis

Chemical Properties	Brown Oil
Uses	Methyl (S)-Pyroglutamate (cas# 4931-66-2) is a compound useful in organic synthesis.

Methyl L-pyroglutamate Preparation Products And Raw materials

Preparation Products

(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone p-toluenesulfonate-->L-Pyroglutamamide-->(+)-(3R,7aS)-Tetrahydro-3-phenyl-3H,5H-pyrrolo1,2-coxaole-5-one-->AT-406-->L-(+)-Glutamic acid hydrochloride

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