Suberic acid

Suberic acid
  • CAS No.:505-48-6
Other grades of this product :
Suberic acid Basic information
Product Name:Suberic acid
Synonyms:KORK ACID;Subericacid,99%;142-144℃;octandioic acid;STRYCHNINE (P);Hexane-1,6-dicarboxylic acid, Suberic acid;Cork Acid 1,6-Hexanedicarboxylic Acid Kork Acid Octanedioic Acid;Suberic aci
CAS:505-48-6
MF:C8H14O4
MW:174.19
EINECS:208-010-9
Product Categories:Pharmaceutical intermediates;Dicarboxylic Acids;Biochemicals and Reagents;Building Blocks;C8;Carbonyl Compounds;Miscellaneous Natural Products;alpha,omega-Alkanedicarboxylic Acids;Carboxylic Acids;Chemical Synthesis;Fatty Acids and conjugates;Fatty Acyls;Lipids;Organic Building Blocks;alpha,omega-Bifunctional Alkanes;Monofunctional & alpha,omega-Bifunctional Alkanes;bc0001
Mol File:505-48-6.mol
Suberic acid Chemical Properties
Melting point 140-144 °C(lit.)
Boiling point 230 °C15 mm Hg(lit.)
density 1.3010 (rough estimate)
vapor pressure 0Pa at 22.85℃
refractive index 1.4370 (estimate)
Fp 203 °C
storage temp. Store below +30°C.
solubility 1.6g/l
form Powder
pka4.52(at 25℃)
color White to cream
PH3.79(1 mM solution);3.27(10 mM solution);2.76(100 mM solution);
Water Solubility 0.6 g/L (20 ºC)
Merck 14,8862
BRN 1210161
Stability:Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, bases.
InChIKeyTYFQFVWCELRYAO-UHFFFAOYSA-N
LogP0.59 at 25℃ and pH7.08
CAS DataBase Reference505-48-6(CAS DataBase Reference)
NIST Chemistry ReferenceOctanedioic acid(505-48-6)
EPA Substance Registry SystemOctanedioic acid (505-48-6)
Safety Information
Hazard Codes Xi
Risk Statements 36-36/37/38
Safety Statements 26-39-36
WGK Germany 1
TSCA Yes
HS Code 29171990
MSDS Information
ProviderLanguage
Octanedioic acid English
ACROS English
SigmaAldrich English
ALFA English
Suberic acid Usage And Synthesis
DescriptionIt was firstly produced by nitric acid oxidation of cork (Latin suber) material and then from castor oil. The oxidation of ricinoleic acid produces, by splitting at the level of the double bond and at the level of the OH group, at the same time, suberic acid (octanedioic acid) and the next homologue azelaic acid. Suberic acid was used in the manufacture of alkyd resins and in the synthesis of polyamides leading to nylon.
Chemical Propertiesoff-white crystalline powder
UsesSuberic Acid is used in the preparation of reduction-sensitive micelles affecting their cellular uptake. This has potential application in delivery of anticancer drugs. It is also used in the fluoresc ent detection of amidinium-carboxylate and amidinium formation.
UsesIn the plastics industry.
UsesSuberic Acid is used in the preparation of reduction-sensitive micelles affecting their cellular uptake. This has potential application in delivery of anticancer drugs. It is also used in the fluorescent detection of amidinium-carboxylate and amidinium formation.
DefinitionChEBI: An alpha,omega-dicarboxylic acid that is the 1,6-dicarboxy derivative of hexane.
Synthesis Reference(s)Journal of the American Chemical Society, 81, p. 3677, 1959 DOI: 10.1021/ja01523a046
Purification MethodsCrystallise it from acetone. It sublimes at 300o without decomposition. [Beilstein 2 IV 2028.]

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