DITHIOURACIL

CAS No.：2001-93-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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DITHIOURACIL Basic information

Product Name:	DITHIOURACIL
Synonyms:	Dithiouracil ,98%;2￡4-Dimercapto;Pyrimidine-2,4(1H,3H)-dithione, 2,4-Dithioxo-1,2,3,4-tetrahydropyrimidine;Pyrimidine-2,4(1H,3H);PYRIMIDINE-2,4-DITHIOL;2,4-dithio-uraci;2,4-Dithioxopyrimidine;Dithiopyrimidine
CAS:	2001-93-6
MF:	C4H4N2S2
MW:	144.22
EINECS:	217-894-5
Product Categories:	Nucleic acids;PYRIMIDINE
Mol File:	2001-93-6.mol

DITHIOURACIL Chemical Properties

Melting point	279-281 °C (dec.) (lit.)
Boiling point	225.6±23.0 °C(Predicted)
density	1.391 (estimate)
refractive index	1.5000 (estimate)
storage temp.	Sealed in dry,2-8°C
form	solid
pka	6.55±0.20(Predicted)
CAS DataBase Reference	2001-93-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Safety Statements	24/25
WGK Germany	3
RTECS	YR0175000
HS Code	29335990

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

DITHIOURACIL Usage And Synthesis

Chemical Properties	yellow crystalline powder
General Description	Dithiouracil is a potential anticancer drug and its redox mechanism and electronic absorption behavior has been investigated in a wide pH range by UV-Vis spectroscopy, cyclic voltammetry and differential pulse voltammetry.

DITHIOURACIL Preparation Products And Raw materials

Raw materials	2-CHLORO-4-METHOXYPYRIMIDINE-->2-Thiouracil-->2,4-Dichloropyrimidine-->Carbamimidothioic acid-->Decahydronaphthalene-->Uracil
Preparation Products	2-MERCAPTOPYRIMIDIN-4-OL-->4-AMINO-2-MERCAPTOPYRIMIDINE

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