2-Oxobutyric acid

2-Oxobutyric acid
  • CAS No.:600-18-0
Other grades of this product :
2-Oxobutyric acid Basic information
Product Name:2-Oxobutyric acid
Synonyms:PROPIONYLFORMIC ACID;2-Ketobutanoic acid;2-oxo-butanoicaci;alpha-Ketobutric acid;alpha-Oxobutyrate;alpha-Oxo-n-butyric acid;Butanoicacid,2-oxo-;Butyric acid, 2-oxo-
CAS:600-18-0
MF:C4H6O3
MW:102.09
EINECS:209-986-9
Product Categories:Pharmaceutical Raw Materials;Aliphatics;Enzyme substrates
Mol File:600-18-0.mol
2-Oxobutyric acid Chemical Properties
Melting point 30-34 °C(lit.)
Boiling point 84 °C20 mm Hg(lit.)
density 1.2000
refractive index 1.3972 (estimate)
FEMA 3723 | 2-OXOBUTYRIC ACID
Fp 179 °F
storage temp. Store at +2°C to +8°C.
solubility H2O: soluble0.1g/mL, clear
form liquid
pka2.5(at 25℃)
Specific Gravity1.3972 (20/4℃)
color White to Almost white
PH3.11(1 mM solution);2.38(10 mM solution);1.79(100 mM solution);
JECFA Number589
BRN 1700514
InChIKeyTYEYBOSBBBHJIV-UHFFFAOYSA-N
CAS DataBase Reference600-18-0(CAS DataBase Reference)
NIST Chemistry ReferenceButanoic acid, 2-oxo-(600-18-0)
EPA Substance Registry System2-Oxobutyric acid (600-18-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37/39-36
RIDADR 1759
WGK Germany 3
HazardClass 8
PackingGroup III
HS Code 29183000
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
2-Oxobutyric acid Usage And Synthesis
Chemical PropertiesCOLOURLESS TO ALMOST COLOURLESS CRYSTALS
Chemical Properties2-Oxobutyric acid has a sweet, brown, caramel, creamy odor.
OccurrenceReported found in beer and black tea.
UsesA substrate for the determination of lactate dehydrogenase isoenzymes.This compound is suitable for lactate dehydrogenase (LDH) related research.
Uses2-Oxobutyric acid (α-ketobutyric acid) may be used as an analytical reference standard for the determination of the analyte in K562 cells by high-performance liquid chromatography with fluorescence detection and in drinking water at low microgram per liter concentrations by ion chromatography technique.
UsesA substrate for the determination of lactate dehydrogenase isoenzymes.
DefinitionChEBI: A 2-oxo monocarboxylic acid that is the 2-oxo derivative of butanoic acid.
Taste threshold valuesTaste characteristics at 25 ppm: sweet, brown, creamy, caramellic with a fatty nuance.
General Description2-Oxobutyric acid is mainly found in the hydrolysates of proteins, reportedly being formed by the degradation of threonine.

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