Fmoc-D-leucine

Fmoc-D-leucine
  • CAS No.:114360-54-2

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
Fmoc-D-leucine Basic information
Product Name:Fmoc-D-leucine
Synonyms:FMOC-D-BETA-LEU-OH;FMOC-D-LEU-OH;FMOC-D-LEUCINE;FMOC-D-LEU;9-FLUORENYLMETHOXYCARBONYL-D-LEUCINE;FMOC-D-LEU-OH 99+%;n-[(9h-fluoren-9-ylmethoxy)carbonyl]-d-leucine;n-fmoc-d-leucine
CAS:114360-54-2
MF:C21H23NO4
MW:353.41
EINECS:252-662-7
Product Categories:Leucine [Leu, L];Fmoc-Amino Acids and Derivatives;Amino Acids (N-Protected);Biochemistry;Fmoc-Amino Acids;Fmoc-Amino acid series;Fluorenes, Flurenones;Amino Acids
Mol File:114360-54-2.mol
Fmoc-D-leucine Chemical Properties
Melting point 155°C
Boiling point 559.8±33.0 °C(Predicted)
density 1?+-.0.06 g/cm3(Predicted)
refractive index 25 ° (C=1, DMF)
storage temp. 2-8°C
pka3.91±0.21(Predicted)
form powder to crystal
color White to Almost white
Water Solubility Insoluble in water.
CAS DataBase Reference114360-54-2(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
F 10
HS Code 29224999
MSDS Information
ProviderLanguage
SigmaAldrich English
Fmoc-D-leucine Usage And Synthesis
Chemical PropertiesWhite powder
UsesA convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.
Fmoc-D-leucine Preparation Products And Raw materials

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