5-IODO-1,3-DIMETHYLURACIL

CAS No.：40738-83-8

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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5-IODO-1,3-DIMETHYLURACIL Basic information

Product Name:	5-IODO-1,3-DIMETHYLURACIL
Synonyms:	5-IODO-1,3-DIMETHYLURACIL;5-IODO-1,3-DIMETHYLURACIL, 99%%;5-Iodo-1,3-dimethylpyrimidine-2,4-dione;5-Iodo-1,3-diMethylpyriMidine-2,4(1H,3H)-dione;5-Iodo-1,3-dimethyl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione, 5-iodo-1,3-dimethyl-;5-IODO-1,3-DIMETHYLURACIL USP/EP/BP
CAS:	40738-83-8
MF:	C6H7IN2O2
MW:	266.04
EINECS:
Product Categories:	pyrimidine;Heterocycle-Pyrimidine series;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks
Mol File:	40738-83-8.mol

5-IODO-1,3-DIMETHYLURACIL Chemical Properties

Melting point	225 °C (dec.)(lit.)
storage temp.	Keep in dark place,Sealed in dry,2-8°C
solubility	DMSO: soluble10mg/mL(lit.)
Sensitive	Light Sensitive
CAS DataBase Reference	40738-83-8

Safety Information

Hazard Codes	Xn
Risk Statements	20/21/22-42/43-63
Safety Statements	22-26-36/37/39-45
WGK Germany	3
HS Code	29335990

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

5-IODO-1,3-DIMETHYLURACIL Usage And Synthesis

Uses	5-Iodo-1,3-dimethyluracil may be used for the synthesis of N-[2-[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)thio]-4-oxo[1]benzothieno[3,2-d]pyrimidin-3(4H)yl]methanesulfonamide.
General Description	The effect of 5-iodo-1,3-dimethyluracil on the incorporation of [¹²⁵I] 5-iodo-2′-deoxyuridine [¹²⁵I radiolabelled IdUrd] in DNA of cancer cells has been studied. Synthesis of 5-iodo-1,3-dimethyluracil from aromatic organomercurials; 5-(acetoxymercurio)-1,3-dimethyluracil or 5,5′-mercuriobis(1,3-dimethyluracil) has been reported.

5-IODO-1,3-DIMETHYLURACIL Preparation Products And Raw materials

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