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| Product Name: | 1,2,3-1H-Triazole | | Synonyms: | LABOTEST-BB LT02056574;1H-1,2,3-TRIAZOLE;1,2,3-TRIAZOLE;1,2,3-1H-TRIAZOLE;TRIAZOLE(1,2,3-);1,2,3-Triazol;1H-1,2,3-Triazol;Osotriazole | | CAS: | 288-36-8 | | MF: | C2H3N3 | | MW: | 69.07 | | EINECS: | 608-262-3 | | Product Categories: | Aromatics;Heterocycles;Building Blocks;Heterocyclic Building Blocks;Intermediates & Fine Chemicals;Pharmaceuticals;Triazoles;bc0001 | | Mol File: | 288-36-8.mol |
| 1,2,3-1H-Triazole Chemical Properties |
| Melting point | 23-25 °C(lit.) | | Boiling point | 203 °C752 mm Hg(lit.) | | density | 1.192 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.498(lit.) | | Fp | 225 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | Acetone, Chloroform, Methanol (Slightly) | | form | Liquid | | pka | 1.17(at 20℃) | | color | Clear colorless to yellow | | Specific Gravity | 1.192 | | Water Solubility | soluble | | FreezingPoint | 21.0 to 24.0 ℃ | | BRN | 104766 | | InChIKey | QWENRTYMTSOGBR-UHFFFAOYSA-N | | CAS DataBase Reference | 288-36-8(CAS DataBase Reference) | | NIST Chemistry Reference | 1H-1,2,3-Triazole(288-36-8) |
| 1,2,3-1H-Triazole Usage And Synthesis |
| Description | 1,2,3-1H-Triazole is a kind of azole compound. It can effectively promote the proton conduction in polymer electrolyte membranes via an intermolecular proton-transfer mechanism. It is also a useful triazole for proteomics research1. It also find use in research as a bioisostere in medicinal chemistry as well as an building block for more complex chemical compounds, including pharmaceutical drugs such as mubritinib and tazobactam2. It is a main class of hetero-cycles because of its extensive range of biological properties such as antimicrobial, anticancer, anti-tubercular, anti-HIV, antimalarial, antibacterial, antifungal, antiviral and anti-diabetic property3.
| | Chemical Properties | clear colorless liquid | | Uses | A basic 5-membered aromatic heterocycle used as a building block for more complex pharmaceutical compounds. There have been recent studies that showed antitumor, antiinflammatory, analgesic, antifunga
l, antibacterial and antiviral activities in bioactive triazoles. | | Uses | It effectively promotes the proton conduction in polymer electrolyte membranes via an intermolecular proton-transfer mechanism. A useful triazole for proteomics research | | Synthesis Reference(s) | The Journal of Organic Chemistry, 62, p. 9177, 1997 DOI: 10.1021/jo971313o | | General Description | 2H-1,2,3-triazole is tautomeric form of 1H-1,2,3-triazole. 1H-1,2,3-triazole effectively promotes the proton conduction in polymer electrolyte membranes via an intermolecular proton-transfer mechanism. |
| 1,2,3-1H-Triazole Preparation Products And Raw materials |
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