2-Diethylaminoethylchloride hydrochloride

2-Diethylaminoethylchloride hydrochloride
  • CAS No.:869-24-9
Other grades of this product :
2-Diethylaminoethylchloride hydrochloride Basic information
Product Name:2-Diethylaminoethylchloride hydrochloride
Synonyms:3,5-DIMETHOXYANISOLE;(2-chloroethyl)diethylaminemonohydrochloride;1-chloro-2-(diethylamine)ethanehydrochloride;2-chloroethyl-n,n-diethylaminehydrochloride;TRISMETHOXYBENZENE;2-chloro-n,n-diethyl-ethanaminhydrochloride;2-Chlorotriethylaminehydrochl;2-chloro-triethylaminhydrochloride
CAS:869-24-9
MF:C6H15Cl2N
MW:172.1
EINECS:212-786-4
Product Categories:Aliphatics;Miscellaneous Reagents
Mol File:869-24-9.mol
2-Diethylaminoethylchloride hydrochloride Chemical Properties
Melting point 50-53 °C(lit.)
Boiling point 255 °C(lit.)
density 1.1919 (rough estimate)
vapor pressure 0Pa at 25℃
refractive index 1.6000 (estimate)
Fp 186 °F
storage temp. Poison room
solubility methanol: 0.1 g/mL, clear, colorless
form Crystalline Powder
color White to slightly beige
PH5 (100g/l, H2O, 20℃)
Water Solubility 2000 g/L (20 ºC)
Sensitive Moisture Sensitive
BRN 3591991
InChIKeyRAGSWDIQBBZLLL-UHFFFAOYSA-N
CAS DataBase Reference869-24-9(CAS DataBase Reference)
EPA Substance Registry SystemDiethyl-(2-chloroethyl)amine hydrochloride (869-24-9)
Safety Information
Hazard Codes Xn,T,Xi,T+
Risk Statements 22-36/37/38-26-24/25-23/24/25
Safety Statements 26-36-45-36/37/39-28A
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS DC2810000
Hazard Note Irritant/Very Toxic
TSCA Yes
HazardClass 6.1
PackingGroup II
HS Code 29211980
Hazardous Substances Data869-24-9(Hazardous Substances Data)
MSDS Information
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2-Diethylaminoethylchloride hydrochloride English
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2-Diethylaminoethylchloride hydrochloride Usage And Synthesis
Chemical Properties2-Diethylaminoethylchloride hydrochloride is colourless to beige crystals
Uses2-Diethylaminoethylchloride hydrochloride is used as intermediate for the syntheses of pharmaceuticals (e.g. amiodarone, butetamate citrate, flurazepam and naftidrofuryl). Product Data Sheet
Uses2-Chloro-N,N-diethylethylamine hydrochloride (65% in water) (DEC 65) is used as intermediate for the syntheses of pharmaceuticals (e.g. amiodarone, butetamate citrate, flurazepam and naftidrofuryl). Product Data Sheet
Uses2-Chloro-N,N-diethylethylamine hydrochloride can be used as an alkylating reagent for the synthesis of:
  • Substituted oxindole derivatives to be used as growth hormone secretagogs.
  • 1-Substituted-5,6-dinitrobenzimidazoles with antimicrobial and antiprotozoal activities.
  • Thiophene containing triarylmethane (TRAM) derivatives to be used as antitubercular agents.
  • Tris(2-(diethylamino)ethyl)amine to be used as a catalyst in combination with CuBr (Et6TREN/CuBr) for atom transfer radical polymerization of n-butyl acrylate.
It can also be used for the derivatization of chitosan to incorporate aminofunctionality onto it at C-6 position.
Purification MethodsCrystallise the salt from absolute MeOH (to remove highly coloured impurities). [Beilstein 4 III 240.]
2-Diethylaminoethylchloride hydrochloride Preparation Products And Raw materials
Raw materialsDiethylaminoethanol
Preparation ProductsN-(3-Trifluoromethylphenyl)piperazine-->1-(2-Methoxyphenyl)piperazine-->CAMYLOFINE DIHYDROCHLORIDE-->Tilorone dihydrochloride

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