2',3'-Dideoxythymidine

2',3'-Dideoxythymidine
  • CAS No.:3416-05-5
Other grades of this product :
2',3'-Dideoxythymidine Basic information
Product Name:2',3'-Dideoxythymidine
Synonyms:3′-Deoxythymidine(DDT);3'-Deoxy-D-thymidine;3''-DESOXYTHYMIDINE;3''-DEOXYTHYMIDINE (2'', 3''-DIDEOXYTHYMIDINE);2μ,3μ-Dideoxythymidine, DDT;1-(2,3-Dideoxy-β-D-ribofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione;1-[5β-(Hydroxymethyl)tetrahydrofuran-2β-yl]-5-methyluracil;Dideoxythymidine
CAS:3416-05-5
MF:C10H14N2O4
MW:226.23
EINECS:2017-001-1
Product Categories:Heterocycle-Pyrimidine series;pyrimidine
Mol File:3416-05-5.mol
2',3'-Dideoxythymidine Chemical Properties
Melting point 155-156 °C(lit.)
alpha 20 º (C=0.6 IN H2O)
density 1.332±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
form Powder
pka9.55±0.10(Predicted)
color White to Pale Yellow
optical activity[α]19/D +20.0°, c = 0.6 in H2O
BRN 21884
InChIKeyXKKCQTLDIPIRQD-JGVFFNPUSA-N
CAS DataBase Reference3416-05-5(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
10-23
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
2',3'-Dideoxythymidine Usage And Synthesis
Uses3’-Deoxythymidine inhibits the ability of bacteriophage T7 to infect Escherichia coli by inhibiting phage DNA synthesis. Also, it is a precursor of DNA polymerase β inhibitor.
UsesResearch tool for antiviral and anticancer studies.
Purification Methods3'-Deoxyuridine is recrystallised from Me2CO/MeOH and is dried in a vacuum. [Michelson & Todd J Chem Soc 816 1955.]

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