3,3-DIFLUOROPYRROLIDINE HYDROCHLORIDE

3,3-DIFLUOROPYRROLIDINE HYDROCHLORIDE
  • CAS No.:163457-23-6

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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3,3-DIFLUOROPYRROLIDINE HYDROCHLORIDE Basic information
Product Name:3,3-DIFLUOROPYRROLIDINE HYDROCHLORIDE
Synonyms:3,3-Difluoropyrrolidine hydrochloride;3,3-Difluoropyrrolidine hydrochloride 97%;GOSO-005;cis-1-Methyl-2-oxo-1,2-dihydro-quinoline-5-carboxylic acid;3,3-DIFLUOROPYRROLIDINE HCL;3,3-DIFLUOROPYRROLIDINE HYDROCHLORIDE;Pyrrolidine, 3,3-difluoro-, hydrochloride (1:1);1-Aza-3,3-difluorocyclopentane
CAS:163457-23-6
MF:C4H8ClF2N
MW:143.56
EINECS:626-850-8
Product Categories:Fluorinated Building Blocks;Halogenated Heterocycles;Building Blocks;Heterocyclic Building Blocks;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles;pharmacetical;Building  Blocks;Halogenated  Heterocycles;Heterocyclic  Building  Blocks;Heterocycles;Miscellaneous Reagents;C4 to C10;Chemical Synthesis;Pyrrolidines;PyrrolidinesHeterocyclic  Building  Blocks
Mol File:163457-23-6.mol
3,3-DIFLUOROPYRROLIDINE HYDROCHLORIDE Chemical Properties
Melting point 128-130°C
storage temp. Inert atmosphere,Room Temperature
Sensitive Hygroscopic
InChIKeyYYVPZQADFREIFR-UHFFFAOYSA-N
CAS DataBase Reference163457-23-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37/39
WGK Germany 3
Hazard Note Irritant
HazardClass IRRITANT, HYGROSCOPIC
HS Code 29339900
MSDS Information
ProviderLanguage
ALFAEnglish
3,3-DIFLUOROPYRROLIDINE HYDROCHLORIDE Usage And Synthesis
Chemical PropertiesBeige solid
Uses3,3-Difluoropyrrolidine hydrochloride can be used as a building block in the synthesis of:
  • Triazole substituted prolyl difluoropyrrolidines as potential inhibitors of dipeptidyl peptidase-4.

  • Dual leucine zipper kinase (DLK) inhibitors.

It can be also used as a reactant in the preparation of cyclic and acyclic β-aminofluoroalkenes via allylic amination using the Pd catalyst.
3,3-DIFLUOROPYRROLIDINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials1-BOC-3,3-DIFLUOROPYRROLIDINE

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