| 2-Thiophenesulfonyl chloride Basic information |
| Product Name: | 2-Thiophenesulfonyl chloride |
| Synonyms: | Thiophene-2-sulphonyl chloride 97%;2-(Chlorosulfonyl)-thiophene;2-Thiophene Sulfonylcloride;2-THIOPHENESULFONYLCHLORIDE,96%;2-Thiophenesulfonic acid chloride;Thiophene-2-sulfonic acid chloride;2-Thiophenesulfonyl chloride,98%;2-Thiophenesulfonyl |
| CAS: | 16629-19-9 |
| MF: | C4H3ClO2S2 |
| MW: | 182.65 |
| EINECS: | 240-677-1 |
| Product Categories: | Sulphonyl Chlorides;Thiophenes & Benzothiophenes;Sulphonyl Chlorides;Building Blocks;Heterocyclic Building Blocks;Thiophenes;Thiophenes & Benzothiophenes;Thiophene&Benzothiophene;Thiophene intermediates;Heterocycle-oher series |
| Mol File: | 16629-19-9.mol |
| 2-Thiophenesulfonyl chloride Chemical Properties |
| Melting point | 30-32 °C(lit.) |
| Boiling point | 130-132 °C14 mm Hg(lit.) |
| density | 1.534 (estimate) |
| refractive index | 1.5722-1.5742 |
| Fp | >110°C |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| form | solid |
| color | White to Almost white |
| Water Solubility | Reacts with water. |
| Sensitive | Moisture Sensitive |
| BRN | 123536 |
| CAS DataBase Reference | 16629-19-9(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Thiophene sulfonyl chloride(16629-19-9) |
| EPA Substance Registry System | 2-Thiophenesulfonyl chloride (16629-19-9) |
| Safety Information |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45-28A-25-27 |
| RIDADR | UN 3261 8/PG 2 |
| WGK Germany | 3 |
| F | 10-21 |
| Hazard Note | Corrosive |
| TSCA | T |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29349990 |
| MSDS Information |
| Provider | Language |
|---|---|
| Thiophene-2-sulfonyl chloride | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 2-Thiophenesulfonyl chloride Usage And Synthesis |
| Chemical Properties | 2-Thiophenesulfonyl chloride is colorless to brown low melting solid or liquid |
| Uses | 2-Thiophenesulfonyl chloride is a compound used in the preparation of various pharmaceuticals. Thiophene-2-sulfonyl Chloride was used as an intermediate in the synthesis of β-Cell apoptosis supressor . |
| Uses | 2-Thiophenesulfonyl chloride has been used in the preparation of 2-((trans-2-phenyl cyclopropyl)sulfonyl)thiophene |
| Synthesis Reference(s) | The Journal of Organic Chemistry, 39, p. 3286, 1974 DOI: 10.1021/jo00936a030 |
| General Description | Kinetics of reactions of 2-thiophenesulfonyl chloride with substituted anilines in methanol has been reported. Kinetics of solvolysis of 2-thiophenesulfonyl chloride in binary solvent mixtures has been studied. |
| 2-Thiophenesulfonyl chloride Preparation Products And Raw materials |
| Raw materials | Chloroform-->Sodium sulfate-->Carbon tetrachloride-->CARBON DIOXIDE-->Chlorosulfonic acid-->Thiophene-->5-iodothiophene-2-sulfonyl chloride-->2-Thiophenesulfonic acid-->2-(TRIBUTYLSTANNYL)THIOPHENE-->Thiophene(SIV) (9CI)-->2-Iodothiophene |
| Preparation Products | Thiophenethiol |
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