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| D-Threonine Basic information |
| D-Threonine Chemical Properties |
| Melting point | 274 °C | | alpha | 28 º (c=6, water) | | Boiling point | 222.38°C (rough estimate) | | density | 1.3126 (rough estimate) | | refractive index | 28 ° (C=3, H2O) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | H2O: soluble | | pka | 2.19±0.10(Predicted) | | form | Crystals or Crystalline Powder | | color | White | | Water Solubility | soluble | | Merck | 9380 | | BRN | 1721643 | | InChIKey | AYFVYJQAPQTCCC-STHAYSLISA-N | | CAS DataBase Reference | 632-20-2(CAS DataBase Reference) |
| D-Threonine Usage And Synthesis |
| Description | D-threonine is the D-form of threonine, which is a kind of amino acids. It can be used for the preparation of enantiomerically pure 1, 3-butanediol. It is also used as the intermediate during the preparation of chiral compounds such as antibiotics. D-threonine is an effective chiral pool reagent which contains an extra stereo-center. For example, people has recently used it as the starting material for total synthesis of protected legionaminic acid.
| | Chemical Properties | white crystalline powder or crystals | | Uses | D-Threonine is the unnatural isomer of L-Threonine (T405500) and is known to inhibit growth and cell wall synthesis of Mycobacterium smegmatis. D-Threonine is also used as a synthetic intermediate for the production of chiral antibiotics. | | Uses | A steroisomer of the proteinogenic amino acid L-threonine. | | Definition | ChEBI: D-threonine is an optically active form of threonine having D-configuration. It has a role as a Saccharomyces cerevisiae metabolite. It is a threonine and a D-alpha-amino acid. It is a conjugate base of a D-threoninium. It is a conjugate acid of a D-threoninate. It is an enantiomer of a L-threonine. It is a tautomer of a D-threonine zwitterion. | | General Description | D-Threonine is sweet and toxic in nature.It acts as an inhibitor of L-threonine dehydratase. | | References | https://www.alfa.com/zh-cn/catalog/B21177/
Ikemi, Masahisa, et al. "D-Threonine Aldolase and Its Application to D -β-Hydroxy-£-Amino Acid Synthesis." (1992).
Paek SM, et al. "Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis." Molecules 21.7(2016):951.
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| D-Threonine Preparation Products And Raw materials |
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