2-Chloro-3-pyridinamine

CAS No.：6298-19-7

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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2-Chloro-3-pyridinamine Basic information

Product Name:	2-Chloro-3-pyridinamine
Synonyms:	3-AMINOCHLOROPYRIDINE;3-AMINO-2-CHLOROPYRIDINE;AKOS MSC-0729;2-Chloro-3-pyridineaMine;Nsc 45407;3-AMINO-2-CHLOROPYRIDINE FOR SYNTHESIS;2-CHLORO-3-AMINOPYRIDINE;2-CHLORO-3-PYRIDYLAMINE
CAS:	6298-19-7
MF:	C5H5ClN2
MW:	128.56
EINECS:	228-572-9
Product Categories:	Building Blocks;C5;Pharmaceutical intermediate;C5 to C6;Chemical Synthesis;Halogenated Heterocycles;PYRIDINE;Amines;Pyridine series;Chloropyridines;Halopyridines;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;blocks;Pyridines;Pyridines, Pyrimidines, Purines and Pteredines;pharmacetical;Heterocyclic Building Blocks;amine \| alkyl chloride;bc0001
Mol File:	6298-19-7.mol

2-Chloro-3-pyridinamine Chemical Properties

Melting point	76-78 °C (lit.)
Boiling point	130-134 °C (12.7517 mmHg)
density	130
refractive index	1.5110 (estimate)
Fp	185 °C
storage temp.	2-8°C
solubility	30g/l
form	Crystalline Powder, Crystals, and/or Chunks
pka	2.42±0.10(Predicted)
color	Off-white to yellow to pink
PH	7 (30g/l, H2O, 20℃)
Water Solubility	Soluble in methanol and water. (30 g/L).
BRN	109814
InChIKey	MEQBJJUWDCYIAB-UHFFFAOYSA-N
CAS DataBase Reference	6298-19-7(CAS DataBase Reference)
NIST Chemistry Reference	3-Amino-2-chloropyridine(6298-19-7)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	UN2811
HazardClass	IRRITANT
HS Code	29333999

MSDS Information

Provider	Language
2-Chloro-3-pyridinamine	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Chloro-3-pyridinamine Usage And Synthesis

Chemical Properties	off-white to yellow to pink crystalline powder,
Uses	It is an intermediate of medicine and agricultural chemicals. It is involved in the Suzuki-Miyaura cross-coupling reactions of heteroaryl compounds.

2-Chloro-3-pyridinamine Preparation Products And Raw materials

Preparation Products

3-Iodopyridin-2-amine-->3-Amino-2-pyridinecarbonitrile-->Pirenzepine-->TAMPRAMINE-->5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one-->2-Chloro-3-(trifluoroMethoxy)pyridine-->3-AMINO-2-PHENYLPYRIDINE-->3-Amino-2-picoline

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