| 2-Amino-3-benzyloxypyridine Basic information |
| Product Name: | 2-Amino-3-benzyloxypyridine |
| Synonyms: | TIMTEC-BB SBB000394;3-(Benzyloxy)pyridin-2-amine, 2-Aminopyridin-3-yl benzyl ether;2-AMino-3-benzyloxypyridine, 98.5% 5GR;2-Amino-3-benzyloxypyridine ,99%;2-Amino-3-benzyloxyp;2-amino-3-(phenylmethoxy)pyridine;2-Amino-3-benzyloxypyridine, 98.5%;NSC 298538 |
| CAS: | 24016-03-3 |
| MF: | C12H12N2O |
| MW: | 200.24 |
| EINECS: | 245-983-9 |
| Product Categories: | Amines;Aromatics;Heterocycles;A-AM;Bioactive Small Molecules;Building Blocks;Pyridines;Bases & Related Reagents;C9 to C46;Heterocyclic Building Blocks;C12;Cell Biology;Chemical Synthesis;Heterocyclic Building Blocks;Pyridines, Pyrimidines, Purines and Pteredines;Heterocyclic Series;Pyridine;Pyridines derivates;Nucleotides and Nucleosides;Nucleotides |
| Mol File: | 24016-03-3.mol |
| 2-Amino-3-benzyloxypyridine Chemical Properties |
| Melting point | 92-94 °C (lit.) |
| Boiling point | 337.96°C (rough estimate) |
| density | 1.1131 (rough estimate) |
| refractive index | 1.6660 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 8.40±0.10(Predicted) |
| color | Green to brown |
| BRN | 392674 |
| CAS DataBase Reference | 24016-03-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Pyridinamine, 3-(phenylmethoxy)-(24016-03-3) |
| Safety Information |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-20/21/22 |
| Safety Statements | 26-37/39-24/25-36/37/39-22,26-36 |
| RIDADR | UN2811 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HS Code | 29221985 |
| MSDS Information |
| Provider | Language |
|---|---|
| 3-Benzyloxy-2-pyridylamine | English |
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| 2-Amino-3-benzyloxypyridine Usage And Synthesis |
| Chemical Properties | Brown crystalline powder |
| Uses | 2-Amino-3-benzyloxypyridine is used in preparation of pyridinyl/pyridazinyloxymethyl substituted Raf kinase inhibitors. |
| Uses | 2-Amino-3-benzyloxypyridine was used in the synthesis of 1-acetyl-2-[2-(3-benzyloxypyridinyl)]iminoimidazolidine. |
| General Description | 2-Amino-3-benzyloxypyridine on condensation with diethyl ethoxymethylene malonate affords 9-benzyloxy-3-ethoxycarbonylpyrido[1,2-a]pyrimidin-4-one. |
| Biochem/physiol Actions | 2-Amino-3-benzyloxypyridine is an inhibitor of mitogen-activated protein kinase p38α activity. |
| 2-Amino-3-benzyloxypyridine Preparation Products And Raw materials |
| Raw materials | 2-Amino-3-hydroxypyridine-->Benzyl chloride-->Benzyl bromide |
| Preparation Products | 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one |
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