TRANS-4-HYDROXYCYCLOHEXANECARBOXYLIC ACID

CAS No.：3685-26-5

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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TRANS-4-HYDROXYCYCLOHEXANECARBOXYLIC ACID Basic information

Product Name:	TRANS-4-HYDROXYCYCLOHEXANECARBOXYLIC ACID
Synonyms:	CIS-4-HYDROXYCYCLOHEXANECARBOXYLIC ACID;TRANS-4-HYDROXYCYCLOHEXANECARBOXYLIC ACID;Hydroxycyclohexanecarboxylicacid;trans-1-Carboxy-4-hydroxycyclohexane;trans-4-Hydroxycyclohexane-1-carboxylic acid;(1r,4r)-4-hydroxycyclohexanecarboxylic acid;trans-4-Hydroxycyclohexanecarboxylic Acid;Cyclohexanecarboxylicacid, 4-hydroxy-, trans-
CAS:	3685-26-5
MF:	C7H12O3
MW:	144.17
EINECS:
Product Categories:	chiral;4-Substituted Cyclohexanecarboxylic Acids;Building Blocks for Liquid Crystals;Chalcones, etc. (Building Blocks for Liquid Crystals);Functional Materials
Mol File:	3685-26-5.mol

TRANS-4-HYDROXYCYCLOHEXANECARBOXYLIC ACID Chemical Properties

Melting point	145°C
Boiling point	308℃
density	1.246
Fp	154℃
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO, Methanol
pka	pK1:4.687 (25°C)
form	Solid
color	White to Off-White
InChIKey	HCFRWBBJISAZNK-IZLXSQMJSA-N

Safety Information

Risk Statements	36/37/38
Safety Statements	26-36/37/39
HS Code	2916200090

MSDS Information

TRANS-4-HYDROXYCYCLOHEXANECARBOXYLIC ACID Usage And Synthesis

Uses	trans-4-Hydroxycyclohexylcarboxylic Acid acts as a reagent in the synthetic preparation of pyrazole-pyrimidine preparation as TTK inhibitors and potential antitumors, Preparation and Janus kinase 1 (JAK1)-selective inhibitory activity of benzimidazole derivatives.

TRANS-4-HYDROXYCYCLOHEXANECARBOXYLIC ACID Preparation Products And Raw materials

Preparation Products

4-(Hydroxymethyl)cyclohexanol(cis- and trans- mixture)-->1-HYDROXY-CYCLOHEXANECARBOXYLIC ACID

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