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| Procyanidin B1 Basic information |
| Product Name: | Procyanidin B1 | | Synonyms: | Procyanidin B1, 97%, from Vitis vinifera Linn.;Procyanidin B1 [Epicatechin (4β→8) catechin];PROCYANIDIN B1;CIS,TRANS''-4,8''-BI-(3,3',4',5,7-PENTAHYDROXYFLAVANE);EPICATECHIN(4B-8)CATECHIN;EPICATECHIN(4BETA->8)CATECHIN;(2R,2'R,3R,3'S,4R)-2,2'-Bis(3,4-dihydroxyphenyl)-4,8'-bichroman-3,3',5,5',7,7'-hexol;(2R,2'R,3R,3'S,4β)-3,3',4,4'-Tetrahydro-2α,2'α-bis(3,4-dihydroxyphenyl)-4,8'-bi[2H-1-benzopyran]-3,3',5,5',7,7'-hexol | | CAS: | 20315-25-7 | | MF: | C30H26O12 | | MW: | 578.52 | | EINECS: | | Product Categories: | Catechins & Tannins;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 20315-25-7.mol |
| Procyanidin B1 Chemical Properties |
| Melting point | 231～232℃ | | Boiling point | 955.3±65.0 °C(Predicted) | | density | 1.705±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,2-8°C | | solubility | Acetone (Slightly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly) | | pka | 9.29±0.60(Predicted) | | form | neat | | color | Pale Brown | | InChIKey | XFZJEEAOWLFHDH-UKWJTHFESA-N |
| Safety Statements | 24/25 | | WGK Germany | 3 | | F | 10-23 | | HS Code | 29329990 |
| Procyanidin B1 Usage And Synthesis |
| Description | Procyanidin B1 is a polyphenol flavonoid existing as a dimer of (+)-catechin and (−)-epicatechin . It inhibits hepatitis C virus RNA replication (EC50 = 72 μM), while (+)-catechin and (−)-epicatechin do not, up to concentrations of 200 μM. Procyanidin B1 (10 μg/ml) prevents phosphorylation of ERK1/2 and the production of reactive oxygen species (ROS) in THP-1 cells. It decreases TNF-α, phosphorylated p38 MAPK, and NF-κB levels following LPS administration. | | Uses | Procyanidins B1 is a B type proanthocyanidins found in ceylon cinnamon and is known to exhibit anti-inflammatory effects. |
| Procyanidin B1 Preparation Products And Raw materials |
| Raw materials | [4,8'-Bi-2H-1-benzopyran]-3,3'-diol, 2,2'-bis[3,4-bis(phenylmethoxy)phenyl]-3,3',4,4'-tetrahydro-5,5',7,7'-tetrakis(phenylmethoxy)-, (2R,2'R,3R,3'S,4R)--->[4,8':4',8''-Ter-2H-1-benzopyran]-3,3',3'',5,5',5'',7,7',7''-nonol, 2,2',2''-tris(3,4-dihydroxyphenyl)-3,3',3'',4,4',4''-hexahydro-, (2R,2'R,2''R,3R,3'S,3''S,4R,4'R)--->Benzoic acid, 3,4,5-trihydroxy-, (2R,2'R,3R,3'S,4R)-2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-3',5,5',7,7'-pentahydroxy[4,8'-bi-2H-1-benzopyran]-3-yl ester-->5,7,3'',4''-Tetra-O-benzylepicatechin-->PROCYANIDIN B7-->L-Epicatechin-->(2R-trans)-2-[3,4-bis(phenylmethoxy)phenyl]-3,4-dihydro-5,7-bis(phenylmethoxy)-2H-1-benzopyran-3-ol-->Cianidanol-->Gallic acid |
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