alpha-Hydroxybenzenepropanoic acid methyl ester

alpha-Hydroxybenzenepropanoic acid methyl ester
  • CAS No.:13673-95-5
Other grades of this product :
alpha-Hydroxybenzenepropanoic acid methyl ester Basic information
Product Name:alpha-Hydroxybenzenepropanoic acid methyl ester
Synonyms:(S)-2-HYDROXY-3-PHENYL-PROPIONIC ACID-METHYL ESTER;(S)-3-PHENYLLACTIC ACID, METHYL ESTER;l-3-phenyl-lactic acid methyl ester;L(-) PHENYLLACTIC ACID METHYL ESTER;L-METHYL 3-PHENYLLACTATE;L-METHYL-BETA-PHENYLLACTATE;METHYL L-3-PHENYLLACTATE;METHYL (S)-2-HYDROXY-3-PHENYLPROPIONATE
CAS:13673-95-5
MF:C10H12O3
MW:180.2
EINECS:
Product Categories:chiral
Mol File:13673-95-5.mol
alpha-Hydroxybenzenepropanoic acid methyl ester Chemical Properties
Melting point 40-45 °C (lit.)
alpha -20.0 º(c=2,H2O)
Boiling point 110-115 °C(Press: 3 Torr)
density 1.150
Fp 120°C
storage temp. Sealed in dry,Room Temperature
pka13.00±0.20(Predicted)
optical activity[α]/D +4.4±0.5°, c = 1% in methanol
CAS DataBase Reference13673-95-5(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29181990
MSDS Information
ProviderLanguage
SigmaAldrich English
alpha-Hydroxybenzenepropanoic acid methyl ester Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powde
UsesMethyl?L-3-phenyllactate can be used:
  • As an intermediate in the synthesis of bortezomib analogs as 20S proteasome inhibitors.
  • As a substrate in the amination of the benzylic C-H bonds and the aminated products are further used to prepare β-lactams.
  • As an intermediate in one of the key synthetic steps for the preparation of YM-254890 analog, a selective Gαq/11 inhibitor.
alpha-Hydroxybenzenepropanoic acid methyl ester Preparation Products And Raw materials
Preparation ProductsD-Phenylalanine methyl ester hydrochloride

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