Product

tert-Butyl rosuvastatin

CAS No.：355806-00-7

Other grades of this product :

tert-Butyl rosuvastatin Basic information

Product Name:	tert-Butyl rosuvastatin
Synonyms:	(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl)methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester;tert-butyl rosuvastatin;tert-Butyl (6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoate;(+)-(3R, 5S)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL-N-METHANESULFONYLAMINO)PYRIMIDIN-5-YL]-(3, 5)-DIHYDROXY-6(E)-HEPTENOATE;Rosuvastatin intermediate R-3;tert-Butyl(+)-(3R,5S)-7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesul fonylamino)pyrimidin-5-yl]-3,5-Dihydroxy-6(E)-Heptenoate;ZD-8;Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N- methylsulfonylamino)pyrimidine-5-yl] -(3R,5S) -dihydroxy -(E)-6-Heptena
CAS:	355806-00-7
MF:	C26H36FN3O6S
MW:	537.64
EINECS:	609-144-4
Product Categories:	Rosuvastatin intermediates;Rosuvastatin Calcium and its intermediates
Mol File:	355806-00-7.mol

tert-Butyl rosuvastatin Chemical Properties

Melting point	136-138oC
Boiling point	704.2±70.0 °C(Predicted)
density	1.259
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated), Methan
pka	13.38±0.20(Predicted)
form	Solid
color	White to Off-White
Stability:	Hygroscopic
CAS DataBase Reference	355806-00-7(CAS DataBase Reference)

Safety Information

MSDS Information

tert-Butyl rosuvastatin Usage And Synthesis

Uses	Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.
Uses	tert-Butyl Rosuvastatin is an impurity of Rosuvastatin (287714-41-4 #CAS), which is a HMG-?CoA reductase inhibitor. In combination of pemafibrate or a salt, it can function as cardiovascular disease medication.

tert-Butyl rosuvastatin Preparation Products And Raw materials

Raw materials

1,3-Dioxane-4-acetic acid, 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2-phenyl-, 1,1-dimethylethyl ester, (4R,6S)--->tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate

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